Description

Benzoic Acid, 2,4,5-Trifluoro-3-(Methylamino)- (9Ci) is a fluorinated benzoic acid derivative, a high-value synthetic intermediate prized for its unique trifluoro and methylamino substitution pattern. This compound is critical for introducing specific fluorine-containing motifs into target molecules, which can dramatically alter their physical, chemical, and biological properties. It is primarily sought by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides, where the fluorine atoms enhance lipophilicity, metabolic stability, and biological activity.
• Material Science Research: Serves as a precursor for synthesizing specialty monomers, ligands, or fluorinated polymers with tailored properties for advanced materials.
• Liquid Crystal & OLED Development: Employed in the creation of fluorinated organic compounds for electronic applications, including liquid crystal displays and organic light-emitting diodes.
• Chemical Biology & Proteomics: Utilized as a probe or linker in biochemical research for studying protein interactions and enzyme mechanisms.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences industry.

Basic Information

Product Name	Benzoic Acid, 2,4,5-Trifluoro-3-(Methylamino)- (9Ci)
CAS No.	127660-43-9
Molecular Formula	C9H7F3NO2
Molecular Weight	218.15 g/mol
Synonyms	3-(Methylamino)-2,4,5-trifluorobenzoic acid; 2,4,5-Trifluoro-3-(methylamino)benzoic acid; 2,4,5-Trifluoro-3-methylaminobenzoic acid; Benzoic acid, 2,4,5-trifluoro-3-(methylamino)-; 127660-43-9; 3-Methylamino-2,4,5-trifluorobenzoic acid
EINECS	Contact for details

Quality Control

Our Benzoic Acid, 2,4,5-Trifluoro-3-(Methylamino)- (9Ci) is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, impurity profile, and residual solvents. Our commitment to quality supports your R&D and scale-up processes with reliable, high-purity material.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. The container must be kept tightly closed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area%)	≥ 99.0%
Single Maximum Impurity	≤ 0.5%
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.