Description

S-(n-Methyl-D3-Carbamoyl)-L-Cysteine is a stable isotope-labeled derivative of the amino acid cysteine, specifically incorporating deuterium atoms in the methyl group of the carbamoyl moiety. This compound is a critical reagent in advanced analytical chemistry, enabling precise quantification and metabolic pathway tracing in complex biological systems. It is primarily utilized by pharmaceutical researchers, contract research organizations (CROs), and diagnostic developers requiring high-fidelity internal standards for mass spectrometry-based assays.

Application

• Mass Spectrometry Internal Standard: Serves as a quantitative reference standard in LC-MS/MS and GC-MS analysis for pharmacokinetic (PK) and pharmacodynamic (PD) studies.
• Metabolomics Research: Used as a tracer to investigate sulfur-containing amino acid metabolism, drug biotransformation pathways, and biomarker discovery.
• Pharmaceutical Development: Essential for the accurate bioanalysis of drug candidates and their metabolites during preclinical and clinical trial stages.
• Clinical Diagnostics: Employed in the development of high-precision clinical assays for monitoring specific metabolic disorders.
• Stable Isotope Labeling: Acts as a building block for synthesizing more complex deuterium-labeled peptides or biochemical probes.

Basic Information

Product Name	S-(n-Methyl-D3-Carbamoyl)-L-Cysteine
CAS No.	127633-26-5
Molecular Formula	C5H6D3N2O3S
Molecular Weight	180.22 g/mol
Synonyms	L-Cysteine, S-[(methyl-d3)aminocarbonyl]-; S-(N-Methyl-d3-carbamoyl)-L-cysteine; (2R)-2-Amino-3-[[(trideuteriomethyl)carbamoyl]sulfanyl]propanoic acid; Methyl-d3-carbamoylcysteine; Deuterated S-Methylcarbamoylcysteine; S-Methylcarbamoyl-D3-L-cysteine; Stable Isotope-Labeled Cysteine Derivative; Internal Standard for Cysteine Metabolites
EINECS	Contact for details

Quality Control

Every batch of S-(n-Methyl-D3-Carbamoyl)-L-Cysteine is manufactured under controlled conditions and undergoes rigorous analytical testing to ensure exceptional isotopic purity and chemical identity. Our quality assurance protocol includes advanced techniques such as NMR, HPLC, and mass spectrometry to verify deuterium incorporation and chemical purity. A comprehensive Certificate of Analysis (COA) detailing isotopic enrichment, assay, and impurity profiles is provided with each shipment to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability and purity. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D3)	≥ 98 atom % D
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.