Description

6-Bromo-5-Methylisatoic Anhydride is a versatile and high-purity heterocyclic building block of significant importance in advanced organic synthesis. Its core value lies in its role as a key precursor for the development of complex pharmaceutical intermediates and active pharmaceutical ingredients (APIs). This compound is primarily needed by research and development chemists and process engineers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific bromine and anhydride functionalities into target molecules.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, where its structural motif contributes to biological activity.
• Organic Light-Emitting Diodes (OLEDs): Serves as a building block for electron-transport materials and emissive layer components in display and lighting technologies.
• Dye and Pigment Manufacturing: Employed in the synthesis of specialized dyes and high-performance pigments due to its fused ring system and bromine substituent.
• Academic and Contract Research: A valuable reagent for methodological studies in organic chemistry, including cross-coupling reactions and heterocycle construction.
• Material Science Research: Investigated for the creation of novel polymers and functional materials with specific electronic or optical properties.

Basic Information

Product Name	6-Bromo-5-Methylisatoic Anhydride
CAS No.	127489-40-1
Molecular Formula	C9H6BrNO3
Molecular Weight	256.05 g/mol
Synonyms	6-Bromo-5-methyl-1H-benzo[d][1,3]oxazine-2,4-dione; 5-Methyl-6-bromoisatoic anhydride; 2H-3,1-Benzoxazine-2,4(1H)-dione, 6-bromo-5-methyl-; 6-Bromo-5-methyl-2,4-dihydro-1H-3,1-benzoxazine-2,4-dione; Isatoic Anhydride, 6-bromo-5-methyl-
EINECS	Contact for details

Quality Control

Our 6-Bromo-5-Methylisatoic Anhydride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high chemical purity and consistent performance. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.