Description

2-Fluoro-4-(Trifluoromethyl)Benzoyl Chloride is a high-purity, reactive aromatic acid chloride derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the strategic combination of fluorine and trifluoromethyl groups, which are essential for modulating the physicochemical properties of target molecules. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring fluorinated aromatic motifs to enhance metabolic stability, bioavailability, and membrane permeability.
• Agrochemical Synthesis: Used in the manufacture of advanced herbicides, fungicides, and insecticides, where the fluorine atoms contribute to improved efficacy and environmental profile.
• Liquid Crystal & OLED Material Production: Serves as a building block for fluorinated components in electronic display materials and organic light-emitting diodes (OLEDs).
• Polymer Chemistry: Employed as a monomer or modifier in the production of specialty polymers, including high-performance resins and coatings with enhanced chemical resistance.
• Custom Synthesis & Contract Research: A valuable reagent for research organizations and CDMOs (Contract Development and Manufacturing Organizations) engaged in custom synthesis projects.
• Dye & Pigment Intermediate: Used in the synthesis of complex fluorinated dyes and pigments for specialized applications.

Basic Information

Item	Detail
Product Name	2-Fluoro-4-(Trifluoromethyl)Benzoyl Chloride
CAS No.	126917-10-0
Molecular Formula	C8H3ClF4O
Molecular Weight	226.56 g/mol
Synonyms	2-Fluoro-α,α,α-trifluoro-p-toluoyl chloride; 4-(Trifluoromethyl)-2-fluorobenzoic acid chloride; 2-Fluoro-4-trifluoromethylbenzoyl chloride; 2-Fluor-4-(trifluormethyl)benzoylchlorid; Benzoic acid, 2-fluoro-4-(trifluoromethyl)-, chloride; 126917-10-0; p-Toluoyl chloride, 2-fluoro-α,α,α-trifluoro-
EINECS	Contact for details

Quality Control

Our 2-Fluoro-4-(Trifluoromethyl)Benzoyl Chloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles where applicable, ensuring reliability for your most demanding synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening. Recommended storage temperature is 2-8°C for long-term stability. Keep away from strong bases, oxidizers, and moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (by GC/HPLC)	≥ 98.0%
Water Content (Karl Fischer)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.