Description

Vasotocin, 1-(β-Mercaptopropionic Acid)-8-Arg-9-(4-Aminofluoresceinyl-Phe)- is a synthetic, fluorescently labeled analog of the neurohypophysial hormone vasotocin, designed for advanced biochemical and pharmacological research. This compound is engineered for high-affinity binding studies, offering a powerful tool for the visualization and quantification of receptor interactions. It is essential for researchers in neuroendocrinology, molecular pharmacology, and drug discovery who require precise, traceable probes for studying vasopressin/oxytocin receptor systems and related signal transduction pathways.

Application

• Receptor Binding Assays: Fluorescent tracer for competitive binding studies and saturation analysis on vasopressin and oxytocin receptor subtypes.
• Cellular Imaging: Visualization of receptor localization, internalization, and trafficking in live or fixed cells using fluorescence microscopy.
• High-Throughput Screening (HTS): Key reagent in fluorescence polarization (FP) or time-resolved fluorescence resonance energy transfer (TR-FRET) assays for drug candidate screening.
• Biophysical Studies: Probe for investigating ligand-receptor interaction kinetics using surface plasmon resonance (SPR) or other biosensor techniques.
• Neuroendocrine Research: Tool for studying the physiological roles of vasotocin-like peptides in model organisms.
• Diagnostic Development: Potential component in the development of fluorescent immunoassays or other in vitro diagnostic applications.

Basic Information

Product Name	Vasotocin, 1-(β-Mercaptopropionic Acid)-8-Arg-9-(4-Aminofluoresceinyl-Phe)-
CAS No.	126660-40-0
Molecular Formula	C71H86N16O16S2
Molecular Weight	1467.67 g/mol
Synonyms	[Mpa1, Arg8, (4-Aminofluoresceinyl-Phe)9]-Vasotocin; Fluorescein-labeled Vasotocin analog; 1-Mercaptopropionic acid-8-arginine-9-(4-aminofluoresceinyl-phenylalanine)-vasotocin; Fluorescent Vasotocin; Vasotocin-FITC analog; AVT fluorescent conjugate; Neurohypophyseal hormone fluorescent probe
EINECS	Contact for details

Quality Control

This high-purity biochemical is manufactured under controlled conditions and subjected to rigorous analytical testing. Quality is assured through multiple orthogonal methods including HPLC for purity assessment and mass spectrometry for identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and fluorescence properties is provided with each batch to ensure consistency and reliability for your critical research applications.

Storage

Preserve in a tightly closed container, protected from light. Store desiccated at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	Yellow to orange lyophilized solid
Identification (HPLC)	Retention time corresponds to reference standard
Identification (MS)	Consistent with molecular weight
Purity (HPLC)	≥ 95%
Absorption Maximum (λmax)	~490 nm
Emission Maximum	~515 nm
Water Content (KF)	≤ 5.0 %

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.