Description

Methyl 3-Amino-4-(Trifluoromethyl)Benzoate is a high-value trifluoromethylated aromatic building block essential for modern synthetic chemistry. This compound is prized for its role in introducing the metabolically stable and lipophilic trifluoromethyl group into target molecules, significantly altering their physicochemical and biological properties. It is a critical intermediate for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, especially in oncology, CNS, and anti-inflammatory therapeutic areas.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides where the CF3 group enhances bioactivity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a building block for specialty chemicals used in electronic displays and organic light-emitting diodes.
• Functional Material Development: Employed in creating advanced polymers, coatings, and dyes with specific performance characteristics.
• Chemical Research & Development: A versatile reagent in academic and industrial R&D labs for exploring new synthetic pathways and creating compound libraries.

Basic Information

Product Name	Methyl 3-Amino-4-(Trifluoromethyl)Benzoate
CAS No.	126541-82-0
Molecular Formula	C9H8F3NO2
Molecular Weight	219.16 g/mol
Synonyms	3-Amino-4-(trifluoromethyl)benzoic acid methyl ester; Methyl 3-amino-α,α,α-trifluoro-p-toluate; Benzoic acid, 3-amino-4-(trifluoromethyl)-, methyl ester; Methyl 3-amino-4-trifluoromethylbenzoate; 3-Amino-4-trifluoromethylbenzoic acid methyl ester; 126541-82-0; Methyl 3-amino-α,α,α-trifluoro-p-toluate
EINECS	Contact for details

Quality Control

Our Methyl 3-Amino-4-(Trifluoromethyl)Benzoate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is easily oxidized and should be stored under an inert atmosphere such as nitrogen or argon for long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.