Description

4-Sulfo-2,3,5,6-Tetrafluorobenzoic Acid is a highly functionalized aromatic compound that serves as a critical building block in advanced chemical synthesis. Its unique structure, featuring both a sulfonic acid and a carboxylic acid group on a perfluorinated benzene ring, makes it a valuable precursor for creating complex molecules with tailored properties. This specialty intermediate is primarily sought by research and development teams in the pharmaceutical and agrochemical sectors for synthesizing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of complex drug molecules, particularly those requiring sulfonamide or fluorinated aromatic motifs to enhance bioavailability and metabolic stability.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides where the introduction of fluorine and sulfonic acid groups can significantly alter biological activity and environmental persistence.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in catalysis, especially in coupling reactions and asymmetric synthesis relevant to fine chemical manufacturing.
• Polymer Modification: Employed to introduce polar, anionic functionalities into polymer backbones, enhancing properties like hydrophilicity, dyeability, or ion-exchange capacity for specialty resins and coatings.
• Material Science Research: Utilized in the development of novel organic electronic materials, metal-organic frameworks (MOFs), and other functional materials where its multifunctional structure allows for precise molecular engineering.
• Chemical Research & Development: A versatile reagent for exploring new synthetic pathways and creating derivatives for biological screening and structure-activity relationship (SAR) studies.

Basic Information

Product Name	4-Sulfo-2,3,5,6-Tetrafluorobenzoic Acid
CAS No.	125662-60-4
Molecular Formula	C7HF4O5S
Molecular Weight	264.14 g/mol
Synonyms	2,3,5,6-Tetrafluoro-4-sulfobenzoic Acid; Benzoic acid, 2,3,5,6-tetrafluoro-4-sulfo-; Tetrafluorosulfobenzoic Acid; 4-Carboxy-2,3,5,6-tetrafluorobenzenesulfonic Acid; Perfluoro-4-sulfobenzoic Acid; 2,3,5,6-Tetrafluoro-4-sulfonylbenzoic Acid; 4-Sulfotetrafluorobenzoic Acid
EINECS	Contact for details

Quality Control

Every batch of 4-Sulfo-2,3,5,6-Tetrafluorobenzoic Acid is manufactured and tested under a strict quality management system to ensure consistency and purity for demanding synthetic applications. We provide comprehensive analytical data, including HPLC purity, NMR confirmation, and elemental analysis. A detailed Certificate of Analysis (COA) is available for each lot upon request, documenting compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Recommended long-term storage temperature is between 2°C and 8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.