Description

11-Hydroxysaxitoxin Sulfate is a potent, naturally occurring neurotoxin analog derived from marine microorganisms. This compound is of significant interest for advanced research in neurobiology and pharmacology, serving as a highly specific sodium channel blocker. It is primarily utilized by research institutions and pharmaceutical developers for receptor binding studies, toxin mechanism research, and the development of analytical standards and detection methods.

Application

• Neuroscience Research: As a specific tool for studying voltage-gated sodium channels and neuronal signal transmission.
• Pharmacological Studies: For investigating the mechanisms of action of paralytic shellfish toxins (PSTs) and developing potential antidotes.
• Analytical Reference Standard: Used in laboratories for the calibration and validation of analytical methods, such as HPLC-MS/MS, for saxitoxin and related toxin detection in food and environmental safety monitoring.
• Toxicology & Safety Testing: Employed in bioassays and competitive binding assays to assess toxin levels and screen for inhibitors.
• Biochemical Reagent: Serves as a key reagent in the study of ion channel function and structure-activity relationships (SAR) within the saxitoxin family.

Basic Information

Product Name	11-Hydroxysaxitoxin Sulfate
CAS No.	125604-84-4
Molecular Formula	C10H19N7O7 • xH2SO4
Molecular Weight	380.31 g/mol (Free base)
Synonyms	11-Hydroxy-STX Sulfate; 11-Hydroxysaxitoxin Hemisulfate; 11β-Hydroxysaxitoxin Sulfate; Hydroxysaxitoxin Sulfate; PST Analog; GTX-3/GTX-4 Epimer; Paralytic Shellfish Poisoning Toxin Derivative; M1 Toxin (related metabolite)
EINECS	Contact for details

Quality Control

Our 11-Hydroxysaxitoxin Sulfate is produced and handled under strict quality protocols to ensure high purity and batch-to-batch consistency for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant standards for high-purity biochemical reagents to support reliable and reproducible scientific outcomes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at -20°C or below for long-term stability. This product is hygroscopic (moisture-sensitive) and light-sensitive; allow the sealed vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (HPLC-MS, NMR)	Conforms to structure
Purity (HPLC)	≥ 95% (Area Percent)
Assay (HPLC)	≥ 90% (by weight)
Water Content (KF)	≤ 5.0 %
Residue on Ignition	≤ 1.0 %

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.