Description

3-Amino-4-(Trifluoromethyl)Benzoic Acid is a high-value trifluoromethylated benzoic acid derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both an amino and a trifluoromethyl group on the aromatic ring, makes it indispensable for creating compounds with enhanced biological activity and physicochemical properties. This intermediate is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the development of new-generation herbicides, fungicides, and insecticides, where the trifluoromethyl group improves lipophilicity and metabolic stability.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science: Building block for advanced polymers and liquid crystals, where its aromatic and fluorinated components contribute to thermal stability and unique optical properties.
• Chemical Research: Versatile reagent in academic and industrial R&D for exploring new synthetic methodologies and creating compound libraries for screening.

Basic Information

Product Name	3-Amino-4-(Trifluoromethyl)Benzoic Acid
CAS No.	125483-00-3
Molecular Formula	C8H6F3NO2
Molecular Weight	205.14 g/mol
Synonyms	4-(Trifluoromethyl)anthranilic Acid; 3-Amino-4-(trifluoromethyl)benzoic Acid; Benzoic acid, 3-amino-4-(trifluoromethyl)-; 2-Amino-α,α,α-trifluoro-m-toluic Acid; 3-Amino-α,α,α-trifluoro-p-toluic Acid; 4-Carboxy-2-(trifluoromethyl)aniline; 2-Amino-4-carboxybenzotrifluoride
EINECS	Contact for details

Quality Control

Our 3-Amino-4-(Trifluoromethyl)Benzoic Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets exacting standards for research and production use. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.