Description

n-(Acetyl-1-14C)-Lactosamine is a radiolabeled derivative of the biologically significant disaccharide lactosamine, where the acetyl group is tagged with carbon-14 at the 1-position. This specific isotopic labeling is crucial for advanced metabolic and pharmacokinetic studies, enabling precise tracking and quantification in complex biological systems. It is an essential research tool for scientists in pharmaceutical development, glycobiology, and biochemistry who require high-purity, well-characterized tracers for autoradiography, LC-MS, and other analytical techniques.

Application

• Tracer in Glycoconjugate Metabolism Studies: Used to investigate the biosynthesis, turnover, and catabolic pathways of glycoproteins and glycolipids containing lactosamine structures.
• Pharmacokinetic (PK) and Absorption, Distribution, Metabolism, and Excretion (ADME) Research: Serves as a critical radiolabeled intermediate for tracking the fate of drug candidates or bioactive compounds in in vitro and in vivo models.
• Enzyme Assay Substrate: Acts as a specific substrate for studying the activity and kinetics of glycosyltransferases, glycosidases, and other enzymes involved in glycan processing.
• Biochemical Pathway Elucidation: Facilitates the mapping of metabolic pathways in cell culture and animal studies, particularly those related to carbohydrate metabolism and cell signaling.
• Quality Control for Radiolabeled Compounds: Can be used as a reference standard in the development and validation of analytical methods (e.g., HPLC, TLC) for other carbon-14 labeled substances.

Basic Information

Product Name	n-(Acetyl-1-14C)-Lactosamine
CAS No.	125455-55-2
Molecular Formula	C14H25NO11 * (¹⁴C)
Molecular Weight	Contact for details
Synonyms	1-¹⁴C-Acetyl-lactosamine; N-Acetyl-1-¹⁴C-lactosamine; Lactosamine, N-[acetyl-1-¹⁴C]-; 2-Acetamido-2-deoxy-4-O-β-D-galactopyranosyl-D-glucose (1-¹⁴C-acetyl); ¹⁴C-Labeled N-Acetyllactosamine; Galβ1-4GlcNAc (1-¹⁴C-Acetyl); N-Acetyl-¹⁴C-lactosamine; Radiolabeled Lactosamine Derivative
EINECS	Contact for details

Quality Control

Every batch of n-(Acetyl-1-14C)-Lactosamine is produced and analyzed under strict quality protocols to ensure traceability, radiochemical purity, and chemical identity. Our products undergo rigorous quality testing to ensure compliance with industry standards for research chemicals. Comprehensive Certificates of Analysis (COA) are provided, detailing parameters such as radiochemical purity, specific activity, chemical purity, and analytical chromatograms.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. For long-term storage, keep desiccated.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR / NMR)	Conforms to structure
Radiochemical Purity (HPLC)	≥ 95%
Specific Activity	Contact for details (mCi/mmol)
Chemical Purity (HPLC)	≥ 90%
Solubility	Soluble in water, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.