Description

D-Valacyclovir Hydrochloride CAS NO 124832-28-6 is the hydrochloride salt of the D-enantiomer of valacyclovir, a key pharmaceutical intermediate and chiral building block. This compound matters significantly for its role in the research and development of enantiomerically pure antiviral agents, ensuring high specificity and efficacy. It is primarily needed by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions focused on chiral synthesis and antiviral drug development.

Application

• As a chiral intermediate in the synthesis of enantiomerically pure antiviral pharmaceuticals.
• For research and development of prodrug formulations targeting herpes viruses and related pathogens.
• In pharmacological studies to investigate the stereospecific metabolism and activity of valacyclovir analogs.
• As a reference standard in analytical method development and quality control for chiral separation techniques (e.g., HPLC, Chiral SFC).
• For use in process chemistry optimization within fine chemical and active pharmaceutical ingredient (API) manufacturing.
• In academic research exploring nucleoside analog chemistry and antiviral mechanisms of action.

Basic Information

Product Name	D-Valacyclovir Hydrochloride
CAS No.	124832-28-6
Molecular Formula	C13H21N6O4·HCl
Molecular Weight	360.81 g/mol
Synonyms	D-Valacyclovir HCl; (2R)-2-[(2-Amino-1,6-dihydro-6-oxo-9H-purin-9-yl)methoxy]ethyl L-valinate hydrochloride; (R)-Valacyclovir Hydrochloride; D-2-[(2-Amino-1,6-dihydro-6-oxo-9H-purin-9-yl)methoxy]ethyl 3-methylbutanoate hydrochloride; L-Valine, 2-[(2-amino-1,6-dihydro-6-oxo-9H-purin-9-yl)methoxy]ethyl ester, hydrochloride, (2R)-; D-Enantiomer of Valacyclovir Hydrochloride
EINECS	Contact for details

Quality Control

Our D-Valacyclovir Hydrochloride is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure compliance with high-purity standards for research and pharmaceutical intermediate applications. A comprehensive Certificate of Analysis (COA) detailing purity, chiral purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (Chiral HPLC)	≥99.0% (D-Enantiomer)
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.