Description

Valacyclovir Hydrochloride is the hydrochloride salt of valacyclovir, a highly effective prodrug of the antiviral acyclovir. This compound is critically important as the active pharmaceutical ingredient (API) in antiviral medications, offering enhanced bioavailability over its parent compound. It is primarily required by pharmaceutical manufacturers for the formulation of antiviral tablets and capsules used in the treatment of herpes simplex virus (HSV) and herpes zoster (shingles).

Application

• Pharmaceutical API: Primary use as the active ingredient in antiviral prescription medications.
• Antiviral Formulations: Manufacture of oral solid dosage forms, including tablets and capsules, for systemic antiviral therapy.
• Treatment of Herpes Simplex Virus (HSV): Used in medications for treating genital herpes and cold sores.
• Treatment of Herpes Zoster: Key component in drugs prescribed for shingles.
• Preventive Therapy: Formulated for suppressive therapy to reduce the frequency of HSV outbreaks.
• Research & Development: Serves as a reference standard and starting material in pharmaceutical R&D for novel antiviral agents.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for generic and branded drug production.

Basic Information

Product Name	Valacyclovir Hydrochloride
CAS No.	124832-27-5
Molecular Formula	C13H20N6O4 • HCl
Molecular Weight	360.80 g/mol
Synonyms	Valacyclovir HCl; L-Valine, 2-[(2-amino-1,6-dihydro-6-oxo-9H-purin-9-yl)methoxy]ethyl ester, monohydrochloride; Valtrex Impurity; BW256U87 hydrochloride; Zelitrex (brand name related); Valtrex (brand name related); 2-[(2-Amino-1,6-dihydro-6-oxo-9H-purin-9-yl)methoxy]ethyl L-valinate hydrochloride
EINECS	Contact for details

Quality Control

Our Valacyclovir Hydrochloride is manufactured under strict quality management systems. It undergoes rigorous analytical testing to ensure compliance with major pharmacopoeial standards, including USP (United States Pharmacopeia) and EP (European Pharmacopoeia) monographs where applicable. Every batch is supported by a comprehensive Certificate of Analysis (COA), detailing purity, identity, and impurity profiles, available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a low-humidity environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	NMT 1.0%
Residue on Ignition	NMT 0.1%
Heavy Metals	NMT 20 ppm
Related Substances (HPLC)	Total impurities NMT 1.0% Any individual impurity NMT 0.5%
Microbial Limits	Conforms to EP/USP requirements

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.