Description

Valaciclovir is the L-valyl ester prodrug of the antiviral agent acyclovir, designed to enhance oral bioavailability. This compound is a critical active pharmaceutical ingredient (API) in the global fight against herpesvirus infections. It is primarily utilized by pharmaceutical manufacturers for the formulation of antiviral medications. Valaciclovir CAS NO 124832-26-4 represents a key intermediate in producing safe and effective therapeutic solutions.

Application

• Antiviral Drug Manufacturing: Primary use as the active pharmaceutical ingredient (API) in prescription antiviral tablets and capsules.
• Treatment of Herpes Simplex Virus (HSV): Used in formulations for treating genital herpes and cold sores (herpes labialis).
• Management of Herpes Zoster (Shingles): A key component in medications for reducing the severity and duration of shingles outbreaks.
• Suppression of Recurrent Genital Herpes: Incorporated into daily suppressive therapy regimens to prevent frequent recurrences.
• Research & Development: Serves as a reference standard and starting material in pharmaceutical R&D for novel antiviral therapies.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for generic and branded drug production.

Basic Information

Product Name	Valaciclovir
CAS No.	124832-26-4
Molecular Formula	C13H20N6O4
Molecular Weight	324.34 g/mol
Synonyms	Valacyclovir; L-Valine, 2-[(2-amino-1,6-dihydro-6-oxo-9H-purin-9-yl)methoxy]ethyl ester; Valtrex (Brand Name); Zelitrex (Brand Name); VACV; BW256U87; 2-[(2-Amino-6-oxo-1,6-dihydro-9H-purin-9-yl)methoxy]ethyl L-valinate; L-Valyl ester of acyclovir
EINECS	Contact for details

Quality Control

Our Valaciclovir is manufactured under strict quality management systems, targeting compliance with major pharmacopoeial standards such as USP and EP. Every batch undergoes rigorous analytical testing including HPLC for assay and purity, determination of related substances, residual solvents, and microbiological examination. A comprehensive Certificate of Analysis (COA) is provided with each shipment to ensure full traceability and specification compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%
Water (Karl Fischer)	≤ 5.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Microbial Enumeration	Meets Ph. Eur. / USP criteria

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.