Description

D-Galactose, [6-3H] is a high-specific-activity, tritium-labeled derivative of the essential monosaccharide D-galactose. This radiolabeled compound is a critical tool for tracing and quantifying galactose metabolism, transport, and incorporation in complex biological systems. It is primarily utilized by researchers and scientists in the fields of biochemistry, molecular biology, and pharmaceutical development for advanced metabolic studies and diagnostic assay development.

Application

• Metabolic Pathway Tracing: Used in in vitro and in vivo studies to elucidate the Leloir pathway and other galactose metabolic routes.
• Enzyme Kinetics & Inhibition Assays: Serves as a substrate for measuring the activity of enzymes like galactokinase, galactose-1-phosphate uridylyltransferase, and other related enzymes.
• Membrane Transport Studies: Employed to investigate the function and kinetics of sugar transporters (e.g., GLUT transporters) in various cell types and tissues.
• Glycobiology Research: Used to study the biosynthesis and turnover of glycoproteins, glycolipids, and proteoglycans by tracing galactose incorporation.
• Diagnostic Development: Acts as a key component in the development of radioenzymatic or radiometric assays for diagnosing disorders of galactose metabolism, such as galactosemia.
• Pharmacokinetic/Pharmacodynamic (PK/PD) Studies: Applied in drug development to study the distribution and metabolism of galactose-based or galactose-metabolism-targeting therapeutics.

Basic Information

Product Name	D-Galactose, [6-3H]
CAS No.	124233-65-4
Molecular Formula	C6H113HO6
Molecular Weight	Contact for details
Synonyms	(6-3H)-D-Galactose; D-[6-3H]Galactose; Tritiated D-Galactose; Galactose-6-t; 6-Tritio-D-galactose; [6-3H]Galactose; D-Galactose (tritium labeled); Radioactive D-Galactose
EINECS	Contact for details

Quality Control

Every batch of D-Galactose, [6-3H] is manufactured and analyzed under strict quality systems to ensure high radiochemical purity and specific activity. Quality assurance includes rigorous testing by HPLC and scintillation counting. A comprehensive Certificate of Analysis (COA), detailing specific activity, radiochemical purity, chemical purity, and solvent composition, is provided with each shipment to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at or below -20°C in the original solvent as supplied. This product is hygroscopic (moisture-sensitive). For long-term storage, it is recommended to keep the vial in a secondary container. Users must handle this material in accordance with all applicable radiation safety regulations and guidelines.

Specification

Item	Specification
Appearance	Clear, colorless solution
Specific Activity	Contact for details (Typical range: 10-40 Ci/mmol)
Radiochemical Purity	≥ 97% (by HPLC)
Chemical Purity	≥ 98% (by HPLC)
Concentration	1 mCi/mL (Contact for other concentrations)
Solvent	Ethanol:Water (9:1 v/v) or as specified
Identification	Co-chromatography with reference standard (HPLC)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.