Description

Pyruvic-3-13C Acid Sodium Salt is a stable, isotopically labeled salt form of pyruvic acid, where the carbon at the 3-position is the stable isotope carbon-13. This compound is essential for advanced research and development, providing a critical tracer for elucidating metabolic pathways and reaction mechanisms. It is primarily utilized by scientists and manufacturers in the pharmaceutical, biotechnology, and analytical chemistry sectors who require high-purity, well-characterized labeled compounds for metabolic studies, NMR spectroscopy, and mass spectrometry.

Application

• Metabolic Pathway Tracing: As a 13C-labeled substrate in cell culture and in vivo studies to track the fate of pyruvate in glycolysis, gluconeogenesis, and the citric acid cycle.
• NMR Spectroscopy: Used as an internal standard or tracer in Nuclear Magnetic Resonance (NMR) experiments to study enzyme kinetics and metabolic flux analysis.
• Mass Spectrometry (MS): Serves as a labeled internal standard for the accurate quantification of pyruvate and related metabolites in LC-MS and GC-MS platforms, improving analytical precision.
• Pharmaceutical Research: Employed in the development and testing of drugs targeting metabolic disorders, cancer (Warburg effect), and diabetes.
• Biochemical Assay Development: Used in enzymatic assays for dehydrogenases and transaminases to study inhibition and activity.
• Stable Isotope Labeling: A key starting material for the synthesis of other 13C-labeled complex molecules and advanced intermediates.

Basic Information

Product Name	Pyruvic-3-13C Acid Sodium Salt
CAS No.	124052-04-6
Molecular Formula	C3H313CNaO3
Molecular Weight	113.04 g/mol (for 13C1 isotopologue)
Synonyms	Sodium Pyruvate-3-13C; 2-Oxopropanoic-3-13C Acid Sodium Salt; Pyruvic Acid-3-13C Sodium Salt; Sodium 2-oxopropanoate-3-13C; [3-13C]Pyruvic Acid Sodium Salt; 13C-Labeled Sodium Pyruvate; NSC 137679-13C
EINECS	Contact for details

Quality Control

Every batch of Pyruvic-3-13C Acid Sodium Salt is produced and analyzed under strict quality management protocols. We ensure high chemical and isotopic purity through advanced analytical techniques. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing parameters such as assay (by NMR or HPLC), isotopic enrichment (by MS), and impurity profile. Our quality system is designed to meet the rigorous standards required for research and regulatory submission support.

Storage

Preserve in a tightly closed container, protected from light. This product is hygroscopic (moisture-sensitive). Store in a cool, dry place at controlled room temperature (15-25°C). For long-term stability, consider storage under an inert atmosphere in a desiccator.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Isotopic Enrichment	≥ 99 atom % 13C
Water Content (KF)	≤ 2.0%
pH (5% solution)	6.0 - 8.0
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.