Description

2-[(1R)-1-Aminoethyl]Phenol Hydrochloride is a chiral, enantiomerically pure organic compound that serves as a critical building block in advanced chemical synthesis. Its value lies in providing a defined stereocenter and functional groups essential for constructing complex molecules with high optical purity. This intermediate is particularly important for pharmaceutical research and development, where it is used in the creation of active pharmaceutical ingredients (APIs), agrochemicals, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of enantiomerically pure drugs, particularly in central nervous system (CNS) and cardiovascular therapeutic areas.
• Agrochemical Synthesis: Used in the development of chiral pesticides and herbicides where specific stereochemistry is required for biological activity.
• Asymmetric Catalyst Ligand Precursor: Serves as a starting material for synthesizing chiral ligands used in asymmetric hydrogenation and other catalytic processes.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances that require precise stereochemical control.
• Academic & Industrial Research: A valuable reagent for methodological development in organic chemistry and medicinal chemistry research programs.

Basic Information

Product Name	2-[(1R)-1-Aminoethyl]Phenol Hydrochloride
CAS No.	123982-75-2
Molecular Formula	C8H12ClNO
Molecular Weight	173.64 g/mol
Synonyms	(R)-1-(2-Hydroxyphenyl)ethylamine Hydrochloride; (1R)-1-(2-Hydroxyphenyl)ethanaminium Chloride; (R)-2-(1-Aminoethyl)phenol HCl; (R)-(-)-1-(2-Hydroxyphenyl)ethylamine Hydrochloride; (R)-o-Hydroxy-α-methylbenzylamine Hydrochloride; (R)-2-(1-Aminoethyl)phenol Hydrochloride; (R)-1-(2-Hydroxyphenyl)ethan-1-amine Hydrochloride
EINECS	Contact for details

Quality Control

Our 2-[(1R)-1-Aminoethyl]Phenol Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for pharmaceutical and advanced synthetic applications. Certificates of Analysis (COA) with detailed specifications for identity, purity, and enantiomeric excess are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.