Description

(S)-(+)-3-Hydroxybutyronitrile is a high-value chiral intermediate, specifically the (S)-enantiomer of 3-hydroxybutyronitrile. This compound is critical for the synthesis of optically active pharmaceuticals and fine chemicals, offering a direct route to introduce a chiral center with high stereochemical purity. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for developing active pharmaceutical ingredients (APIs), chiral ligands, and advanced materials.

Application

• Pharmaceutical Synthesis: A key chiral building block for the production of β-blockers, statins, and other enantiomerically pure drugs.
• Agrochemical Intermediates: Used in the manufacture of chiral pesticides and herbicides to enhance efficacy and reduce environmental impact.
• Fine Chemical Production: Serves as a precursor for chiral alcohols, amino acids, and other specialty chemicals via further chemical transformations.
• Asymmetric Catalysis: Employed in the synthesis of chiral ligands and catalysts for asymmetric synthesis applications.
• Biochemical Research: Used as a standard or reagent in enzymatic studies and metabolic pathway research.
• Polymer Chemistry: Potential monomer or modifier for creating polymers with specific optical or physical properties.

Basic Information

Product Name	(S)-(+)-3-Hydroxybutyronitrile
CAS No.	123689-95-2
Molecular Formula	C₄H₇NO
Molecular Weight	85.10 g/mol
Synonyms	(S)-3-Hydroxybutyronitrile; (S)-3-Hydroxybutanenitrile; (S)-3-Hydroxybutyric acid nitrile; (S)-3-Cyano-1-propanol; (S)-3-Hydroxypropyl cyanide; (S)-1-Cyano-2-propanol; (S)-Oxybutyronitrile; (S)-3-HBN
EINECS	Contact for details

Quality Control

Our (S)-(+)-3-Hydroxybutyronitrile is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for synthetic applications. A Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profile is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, the container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen) to minimize moisture absorption and degradation. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.