Description

(2S)-2-(4-Bromophenyl)-2-Hydroxyacetic Acid >99% Ee is a high-purity, single-enantiomer chiral building block of significant importance in asymmetric synthesis. Its value lies in its defined stereochemistry, which is critical for producing optically active pharmaceutical intermediates and fine chemicals. This compound is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing new active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and cardiovascular drug candidates.
• Asymmetric Catalyst Ligand Precursor: Used in the development and preparation of chiral ligands for metal-catalyzed asymmetric reactions.
• Agrochemical Synthesis: Serves as a building block for creating chiral herbicides, fungicides, and plant growth regulators with enhanced efficacy and environmental profile.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances where optical purity is essential.
• Academic & Industrial Research: A valuable reagent for methodological development in organic chemistry and medicinal chemistry research programs.
• Reference Standard: Used as a high-purity standard for analytical method development and quality control in chiral separation techniques like HPLC and SFC.

Basic Information

Product Name	(2S)-2-(4-Bromophenyl)-2-Hydroxyacetic Acid >99% Ee
CAS No.	123484-90-2
Molecular Formula	C8H7BrO3
Molecular Weight	231.05 g/mol
Synonyms	(S)-2-(4-Bromophenyl)-2-hydroxyacetic acid; (S)-(-)-4-Bromomandelic acid; (S)-α-Hydroxy-4-bromobenzeneacetic acid; L-(-)-4-Bromomandelic acid; (2S)-2-Hydroxy-2-(4-bromophenyl)acetic acid; (S)-4-Bromomandelic acid; (S)-O-Bromomandelic acid; (S)-2-(p-Bromophenyl)-2-hydroxyacetic acid
EINECS	Contact for details

Quality Control

Our (2S)-2-(4-Bromophenyl)-2-Hydroxyacetic Acid is produced under strict quality management systems. Every batch undergoes comprehensive analytical testing, including chiral HPLC for enantiomeric excess (Ee) verification, to ensure it meets the specified >99% Ee purity and other critical parameters. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency, supporting your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider using a desiccator or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.