Description

Ethyl 2,3,4,5-Tetrafluorobenzoate is a high-purity fluorinated aromatic ester, serving as a critical building block in advanced organic synthesis. Its value lies in the strategic placement of fluorine atoms on the aromatic ring, which significantly alters the electronic and steric properties of downstream molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients with enhanced metabolic stability and bioavailability.

Application

• Pharmaceutical Intermediate: A key synthon for the preparation of fluorinated drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and pesticides, where fluorine incorporation improves lipophilicity and target binding.
• Liquid Crystal Materials: Serves as a precursor for fluorinated mesogens in the production of high-performance liquid crystal displays (LCDs).
• Organic Electronics: Employed in the synthesis of fluorinated organic semiconductors and charge-transport materials for OLEDs and solar cells.
• Advanced Polymer Modifiers: Acts as a monomer or grafting agent to introduce fluorine into polymer backbones, enhancing chemical resistance and surface properties.
• Chemical Research & Development: A versatile reagent for exploring novel fluorination reactions and creating compound libraries for high-throughput screening.

Basic Information

Product Name	Ethyl 2,3,4,5-Tetrafluorobenzoate
CAS No.	122894-73-9
Molecular Formula	C9H6F4O2
Molecular Weight	222.14 g/mol
Synonyms	Benzoic acid, 2,3,4,5-tetrafluoro-, ethyl ester; Ethyl 2,3,4,5-tetrafluorobenzoate; 2,3,4,5-Tetrafluorobenzoic acid ethyl ester; Ethyl tetrafluorobenzoate; NSC 339063; Ethyl perfluorobenzoate (common name); Tetrafluorobenzoic acid ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 2,3,4,5-Tetrafluorobenzoate is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure it meets the highest standards of purity and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flames. The container should be kept tightly sealed in a dry environment to minimize moisture absorption.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Related Substances (HPLC)	Total impurities ≤2.0%
Density (at 20°C)	~1.4 g/cm³

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.