Description

Phoslactomycin E CAS NO 122856-29-5 is a specialized natural product belonging to the phoslactomycin class of compounds, characterized by a unique phospho-lactone structure. This compound is of significant interest in pharmaceutical research and development due to its potent biological activity, particularly as a selective inhibitor of protein phosphatases. It serves as a critical reference standard and a valuable building block for researchers in the fields of medicinal chemistry, chemical biology, and oncology.

Application

• Pharmaceutical Research & Development: As a key reference standard for analytical method development, quality control, and biological screening.
• Medicinal Chemistry: Used as a lead compound or a sophisticated intermediate for the synthesis of novel drug candidates targeting specific cellular pathways.
• Chemical Biology Studies: Employed as a molecular probe to investigate protein phosphatase function and related signal transduction mechanisms in cell biology.
• Oncology Research: Investigated for its potential anti-cancer properties and its role in modulating cell cycle progression and apoptosis.
• Academic & Institutional Research: Supplied to universities and research institutes for fundamental studies in natural product chemistry and biochemistry.
• Biotech Catalyst: Serves as a crucial tool in high-throughput screening assays to identify new therapeutic targets.

Basic Information

Product Name	Phoslactomycin E
CAS No.	122856-29-5
Molecular Formula	C₂₅H₃₉NO₈P
Molecular Weight	512.55 g/mol
Synonyms	Phoslactomycin E; FR-901512; Phosphazomycin B; (2E,4E,6E,8E)-9-[(2R,3S,4S,5S,6R)-4,5-Dihydroxy-6-methyl-3-(phosphonooxy)oxan-2-yl]-N-[(1S,2R)-1-hydroxy-1-phenylpropan-2-yl]-3,7-dimethylnona-2,4,6,8-tetraenamide; L-156,602; Antibiotic FR 901512
EINECS	Contact for details

Quality Control

Every batch of Phoslactomycin E is manufactured and analyzed under strict quality management protocols to ensure identity, purity, and consistency. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with research-grade standards. A comprehensive Certificate of Analysis (COA) detailing purity, assay results, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry, moisture-free environment. The product is hygroscopic (moisture-sensitive) and light-sensitive. For long-term storage, consider storage under an inert atmosphere. Allow the sealed vial to warm to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 2.0%
Specific Rotation	Contact for details
Solubility	Soluble in DMSO, Methanol; Slightly soluble in Water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.