Description

Methyl (2R,3S)-(+)-2,3-Dihydroxy-3-Phenylpropionate is a high-purity chiral building block of significant importance in asymmetric synthesis. This compound serves as a key intermediate for the production of complex pharmaceutical actives and fine chemicals, enabling the construction of molecules with precise stereochemistry. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing new drugs and advanced materials.

Application

• Pharmaceutical Intermediate: Critical chiral synthon for the synthesis of protease inhibitors, antiviral agents, and other bioactive molecules.
• Asymmetric Catalysis Research: Used as a starting material or ligand precursor in the development of novel catalytic systems.
• Agrochemical Synthesis: Building block for creating enantiomerically pure herbicides and plant growth regulators.
• Fine Chemical Production: Intermediate in the manufacture of flavors, fragrances, and advanced polymers requiring specific stereocenters.
• Academic & R&D: Serves as a standard or reagent in university and corporate laboratories for methodological studies in organic chemistry.

Basic Information

Product Name	Methyl (2R,3S)-(+)-2,3-Dihydroxy-3-Phenylpropionate
CAS No.	122743-18-4
Molecular Formula	C10H12O4
Molecular Weight	196.20 g/mol
Synonyms	(2R,3S)-Methyl 2,3-Dihydroxy-3-phenylpropanoate; (+)-(2R,3S)-Methyl 2,3-Dihydroxy-3-phenylpropionate; (2R,3S)-Methyl 3-Phenylglycerate; Methyl (R,S)-Phenylglycerate; (2R,3S)-3-Phenylglyceric Acid Methyl Ester; L-threo-Methyl 3-phenylglycerate; (2R,3S)-2,3-Dihydroxy-3-phenylpropionic Acid Methyl Ester
EINECS	Contact for details

Quality Control

Our production of Methyl (2R,3S)-(+)-2,3-Dihydroxy-3-Phenylpropionate adheres to stringent quality protocols to ensure batch-to-batch consistency and high enantiomeric purity. Each lot is characterized using advanced analytical techniques including chiral HPLC, NMR, and optical rotation measurement. Certificates of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Specific Optical Rotation	+15° to +20° (c=1 in MeOH)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.