Description

2-Amino-3-cyclopentene-1-carboxylic acid is a specialized non-proteinogenic amino acid derivative featuring a cyclopentene ring, making it a valuable chiral building block and intermediate in advanced organic synthesis. Its unique constrained structure is crucial for modulating the conformation and biological activity of target molecules. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutics, peptide mimetics, and complex chemical libraries.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for constrained peptides and enzyme inhibitors.
• Peptidomimetics & Drug Discovery: Used to introduce conformational constraints into peptide backbones, enhancing metabolic stability and receptor selectivity in drug candidate molecules.
• Chemical Biology & Proteomics: Employed as a building block for synthesizing specialized amino acid analogs to study protein structure, function, and protein-protein interactions.
• Agrochemical Research: Acts as an intermediate in the synthesis of novel compounds with potential herbicidal or plant growth regulatory activity.
• Material Science: Investigated as a monomer or precursor for synthesizing novel polymers with specific functional properties.
• Academic & Contract Research: A valuable reagent for methodological development in asymmetric synthesis and for creating diverse compound libraries for screening.

Basic Information

Product Name	2-Amino-3-cyclopentene-1-carboxylic Acid
CAS No.	122022-98-4
Molecular Formula	C6H9NO2
Molecular Weight	127.14 g/mol
Synonyms	2-Amino-1-cyclopentene-3-carboxylic Acid; (1R,2S)-2-Amino-3-cyclopentene-1-carboxylic Acid; 3-Cyclopentene-1-carboxylic acid, 2-amino-; 2-Amino-3-cyclopentenecarboxylic Acid; Cyclopentenylglycine; 2-Azabicyclo[3.3.0]oct-3-ene-1-carboxylic acid derivative; cis-2-Amino-1-cyclopentene-3-carboxylic acid
EINECS	Contact for details

Quality Control

We supply 2-Amino-3-cyclopentene-1-carboxylic acid in high-purity grades suitable for research and development. Our products undergo rigorous quality testing, including chromatographic purity analysis and chiral purity verification, to ensure batch-to-batch consistency and compliance with customer specifications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee (enantiomeric excess)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.