Description

Tetranor-12(S)-Hete CAS NO 121842-79-3 is a specialized prostanoid metabolite and a key analytical reference standard in biomedical research. This compound is crucial for the precise quantification and study of eicosanoid metabolic pathways and related physiological processes. It is primarily utilized by research institutions, pharmaceutical R&D departments, and diagnostic manufacturers focused on inflammation, cardiovascular, and metabolic disease research.

Application

• Biomedical Research Standard: Serves as a critical reference compound for the development and validation of analytical methods, particularly liquid chromatography-mass spectrometry (LC-MS/MS), for eicosanoid profiling.
• Metabolomics Studies: Used in targeted metabolomics to investigate arachidonic acid metabolism, oxidative stress, and inflammatory biomarker discovery.
• Pharmaceutical Development: Employed as an analytical standard in pharmacokinetic and pharmacodynamic studies for drugs targeting prostanoid pathways.
• Clinical Diagnostics: Acts as a calibrator and quality control material in the development of in-vitro diagnostic (IVD) assays for specific eicosanoid metabolites.
• Biochemical Pathway Analysis: Essential for in-vitro and in-vivo studies aimed at elucidating the role of specific HETE metabolites in cell signaling and disease mechanisms.

Basic Information

Product Name	Tetranor-12(S)-Hete
CAS No.	121842-79-3
Molecular Formula	C16H26O3
Molecular Weight	266.38 g/mol
Synonyms	5,8,10-Heptadecatrienoic acid, 12-hydroxy-7,14,15,16-tetranor-, (5Z,8Z,10E,12S)-; 12(S)-HETE tetranor metabolite; 12(S)-HETE ω-oxidation metabolite; Tetranor-12-hydroxy-5,8,10-heptadecatrienoic acid; 12(S)-HETE ω-carboxy metabolite (further oxidized form); 12(S)-HETE ω/β-oxidation product; 16-COOH-12(S)-HETE tetranor; 12(S)-HETE-d4 internal standard analog (common related compound).
EINECS	Contact for details

Quality Control

Our Tetranor-12(S)-Hete is produced under strict quality management protocols to ensure the high purity and consistency required for sensitive analytical applications. Each batch is characterized using advanced techniques including NMR, HPLC, and mass spectrometry to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing batch-specific results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation. Store away from strong acids and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid or oil
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to reference standard
Purity (HPLC)	≥ 95% (Area %)
Purity (NMR)	Conforms to structure
Solubility	Soluble in ethanol, DMSO, acetonitrile

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.