Description

(R)-(+)-2-(Methoxymethyl)-1-Pyrrolidinecarboxaldehyde is a high-purity chiral building block and key intermediate in organic synthesis. Its value lies in its role as a versatile precursor for introducing the (R)-2-(methoxymethyl)pyrrolidine moiety, a privileged scaffold found in numerous biologically active molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries, particularly for the development of chiral catalysts, ligands, and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of complex drug molecules, including antiviral agents and enzyme inhibitors.
• Asymmetric Catalysis: Used in the preparation of chiral ligands and organocatalysts for enantioselective synthesis.
• Agrochemical Research: Serves as a building block for developing novel, chiral active ingredients with improved efficacy and selectivity.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of specialty chemicals, flavors, and fragrances requiring high enantiomeric purity.
• Academic & R&D: A valuable reagent for methodological development in organic chemistry and medicinal chemistry research programs.

Basic Information

Product Name	(R)-(+)-2-(Methoxymethyl)-1-Pyrrolidinecarboxaldehyde
CAS No.	121817-71-8
Molecular Formula	C7H13NO2
Molecular Weight	143.18 g/mol
Synonyms	(R)-2-(Methoxymethyl)pyrrolidine-1-carbaldehyde; (R)-(+)-1-Formyl-2-(methoxymethyl)pyrrolidine; (R)-N-Formyl-2-(methoxymethyl)pyrrolidine; (R)-1-[(2-Methoxymethyl)pyrrolidinyl]methanal; (R)-2-Methoxymethyl-1-pyrrolidinecarboxaldehyde; (R)-Proline Methyl Ether Aldehyde Derivative; (R)-MOP Aldehyde
EINECS	Contact for details

Quality Control

Our (R)-(+)-2-(Methoxymethyl)-1-Pyrrolidinecarboxaldehyde is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high chemical purity. Production adheres to cGMP guidelines where applicable. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles. We support compliance with global regulatory standards, including REACH.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is easily oxidized; for long-term storage, consider maintaining under an inert atmosphere (e.g., nitrogen or argon). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.