Description

Didanosine is a synthetic purine nucleoside analog with significant antiviral activity. This compound is a critical active pharmaceutical ingredient (API) used in the formulation of antiviral medications. It is primarily required by pharmaceutical manufacturers and research institutions engaged in the development and production of treatments for viral infections.

Application

• Antiviral Drug Manufacturing: Primary use as the active pharmaceutical ingredient (API) in the synthesis of antiviral medications.
• Pharmaceutical Research & Development: Serves as a key reference standard and intermediate in the discovery and development of new nucleoside-based therapeutics.
• Biochemical Research: Used as a tool compound in virology and molecular biology studies to investigate viral replication mechanisms and enzyme inhibition.
• Formulation Development: Employed in the development of various dosage forms, including tablets, capsules, and pediatric suspensions.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of finished drug products.
• Analytical Standard: Utilized as a high-purity standard for quality control and analytical method development (e.g., HPLC, LC-MS) in pharmaceutical laboratories.

Basic Information

Product Name	Didanosine
CAS No.	121154-53-8
Molecular Formula	C10H12N4O3
Molecular Weight	236.23 g/mol
Synonyms	2',3'-Dideoxyinosine; ddI; Dideoxyinosine; BM 41-002; NSC 612049; Videx (brand name); (2R,5S)-5-(6-Amino-9H-purin-9-yl)-2-(hydroxymethyl)tetrahydrofuran-3-ol
EINECS	Contact for details

Quality Control

Our Didanosine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets high-purity pharmaceutical standards, including identity, potency, and impurity profile verification. Certificates of Analysis (COA) detailing specifications such as assay, related substances, residual solvents, and microbiological quality are provided with every shipment to ensure full traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Heavy Metals	≤ 20 ppm
Microbiological Enumeration	Complies with Ph. Eur. 2.6.12 / USP <61>

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.