Description

1,3-Bis(Di-tert-Butylphosphino)Propane is a specialized, high-purity organophosphorus ligand widely used in homogeneous catalysis. This compound matters for its exceptional electron-donating properties and steric bulk, which are critical for stabilizing reactive metal centers and enhancing catalytic performance in demanding chemical transformations. It is primarily needed by R&D chemists and process engineers in the pharmaceutical, agrochemical, and advanced materials industries for developing and scaling up efficient synthetic routes.

Application

• Homogeneous Catalysis: As a key ligand in cross-coupling reactions (e.g., Suzuki-Miyaura, Heck, Buchwald-Hartwig) for C-C and C-N bond formation.
• Pharmaceutical Intermediates: Enabling the synthesis of complex, high-value drug candidates and active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in catalytic processes to create novel pesticides, herbicides, and plant growth regulators.
• Polymerization Catalysis: Serving as a ligand in olefin polymerization and other polymer synthesis catalysts.
• Fine Chemical Production: Facilitating selective hydrogenation, hydroformylation, and other specialty chemical syntheses.
• Academic & Industrial Research: A valuable tool for developing new catalytic methodologies and exploring reaction mechanisms.

Basic Information

Product Name	1,3-Bis(Di-tert-Butylphosphino)Propane
CAS No.	121115-33-1
Molecular Formula	C19H42P2
Molecular Weight	332.48 g/mol
Synonyms	DTBPP; 1,3-Bis(di-tert-butylphosphino)propane; Di-tert-butylphosphinopropane; Bis(di-tert-butylphosphino)propane; 1,3-Propanediylbis[bis(1,1-dimethylethyl)phosphine]; (t-Bu)2P(CH2)3P(t-Bu)2; Ligand DTBP
EINECS	Contact for details

Quality Control

Our 1,3-Bis(Di-tert-Butylphosphino)Propane is manufactured under stringent quality control protocols to ensure batch-to-batch consistency and high purity, essential for reproducible catalytic performance. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality management system adheres to cGMP principles where applicable, supporting its use in regulated synthesis pathways.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C to minimize oxidation and degradation. The container should be kept in a cool, dry, and well-ventilated area, away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Solubility	Soluble in common organic solvents (THF, toluene, hexane)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.