Description

Celgosivir is a potent and selective α-glucosidase I inhibitor, a compound of significant interest in antiviral and biomedical research. Its primary value lies in its ability to interfere with the N-linked glycosylation pathway of viral envelope proteins, which is crucial for the infectivity of a range of viruses. This mechanism makes it a critical research tool for virologists and pharmaceutical developers targeting enveloped viruses, including influenza, dengue, and hepatitis. Researchers in antiviral drug discovery, glycobiology, and preclinical development are the primary users of this high-purity biochemical.

Application

• Antiviral Research: Used as a reference standard and active compound in studies targeting the replication of enveloped viruses like influenza, dengue, and hepatitis B/C.
• Glycobiology Studies: Serves as a specific inhibitor to study N-linked oligosaccharide processing and its role in protein folding, secretion, and function.
• Drug Discovery & Development: Employed in high-throughput screening (HTS) and lead optimization programs for novel antiviral therapeutics.
• Mechanistic Pharmacology: Utilized to investigate the role of host glycosylation enzymes as targets for broad-spectrum antiviral strategies.
• Biochemical Assay Development: Acts as a key control compound in developing and validating enzymatic assays for α-glucosidase I activity.
• Academic & Institutional Research: Fundamental research tool in university and government laboratories studying viral pathogenesis and host-pathogen interactions.

Basic Information

Product Name	Celgosivir
CAS No.	121104-96-9
Molecular Formula	C₁₀H₁₉NO₄
Molecular Weight	217.26 g/mol
Synonyms	6-O-Butanoylcastanospermine; MDL 28574; BCS; Celgosivir Hydrochloride (salt form); (1S,6S,7R,8R,8aR)-1,6,7,8-Tetrahydroxyoctahydroindolizine-7-butyl ester; Butanoylcastanospermine; α-glucosidase I inhibitor; Anti-influenza agent
EINECS	Contact for details

Quality Control

Our Celgosivir is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot undergoes comprehensive analytical testing including HPLC for purity and identity confirmation. A detailed Certificate of Analysis (COA) providing full specifications and test results is supplied with every shipment to guarantee traceability and compliance with your research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤2.0%
Solubility	Soluble in DMSO, Methanol; Slightly soluble in Water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.