Description

5-Methyl-2-(Trifluoromethyl)Benzoic Acid is a versatile fluorinated aromatic carboxylic acid building block, prized for its unique combination of steric and electronic properties imparted by the methyl and trifluoromethyl substituents. This compound is essential for the synthesis of advanced materials and active pharmaceutical ingredients (APIs), where its structure can significantly influence biological activity and material stability. It is a critical intermediate for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel compounds with enhanced performance characteristics.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for molecules targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group improves lipophilicity and biological activity.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorinated components in electronic display materials and organic light-emitting diodes (OLEDs), enhancing thermal stability and electronic properties.
• Polymer Modification: Incorporated as a monomer or additive to create specialty polymers with improved chemical resistance, weatherability, and surface properties.
• Organic Synthesis & Catalysis: Employed as a ligand precursor or a structurally rigid acid component in metal-organic frameworks (MOFs) and catalytic systems.
• Chemical Research & Development: A valuable reagent for academic and industrial R&D in medicinal chemistry and material science for structure-activity relationship (SAR) studies.

Basic Information

Product Name	5-Methyl-2-(Trifluoromethyl)Benzoic Acid
CAS No.	120985-68-4
Molecular Formula	C9H7F3O2
Molecular Weight	204.15 g/mol
Synonyms	2-(Trifluoromethyl)-5-methylbenzoic acid; 5-Methyl-α,α,α-trifluoro-o-toluic acid; 2-Trifluoromethyl-5-methylbenzoic acid; 5-Methyl-2-trifluoromethylbenzoic acid; m-Toluic acid, 2-(trifluoromethyl)-; Benzoic acid, 5-methyl-2-(trifluoromethyl)-; 120985-68-4
EINECS	Contact for details

Quality Control

Our 5-Methyl-2-(Trifluoromethyl)Benzoic Acid is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) documenting all critical parameters are available upon request to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.