Description

Alvameline CAS NO 120241-31-8 is a selective muscarinic receptor agonist, a compound of significant interest in pharmaceutical research and development. Its primary value lies in its potential therapeutic applications for neurological and cognitive disorders. This product is essential for researchers and manufacturers in the pharmaceutical industry, particularly those focused on developing treatments for conditions like Alzheimer's disease and other central nervous system ailments.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs) targeting muscarinic receptors.
• Neurological Research: Used in preclinical and clinical studies to investigate treatments for Alzheimer's disease and related dementias.
• Cognitive Disorder Therapeutics: Development of potential medications aimed at improving memory, learning, and cognitive function.
• Receptor Binding Assays: Serves as a reference standard or ligand in biochemical assays to study muscarinic receptor pharmacology.
• Drug Discovery Programs: A critical compound in medicinal chemistry for designing and optimizing new cholinergic agents.
• GMP Manufacturing: Sourced for the production of clinical trial materials under Good Manufacturing Practice guidelines.

Basic Information

Product Name	Alvameline
CAS No.	120241-31-8
Molecular Formula	C23H30N2O3S
Molecular Weight	414.56 g/mol
Synonyms	Alvameline; (3R)-1-Azabicyclo[2.2.2]oct-3-yl (2S)-2-hydroxy-2,2-di(thiophen-2-yl)acetate; LU 25-109; LU-25-109; 3-Quinuclidinyl 2-Hydroxy-2,2-di(2-thienyl)acetate; (R)-3-Quinuclidinol α-Hydroxy-α,α-di-2-thienylacetate
EINECS	Contact for details

Quality Control

Our Alvameline is manufactured and tested to meet high-purity standards suitable for research and pharmaceutical applications. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, MS). We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters to ensure traceability and compliance with your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under inert atmosphere or in a desiccator to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.