Description

2-Piperidinecarboxylicacid,3-Hydroxy-,(2R,3S)-(9Ci) is a high-purity, stereochemically defined chiral building block of significant importance in advanced organic synthesis. Its precise stereochemistry makes it a critical intermediate for the development of novel pharmaceuticals and bioactive compounds. This product is essential for research and production chemists in the pharmaceutical, agrochemical, and fine chemical industries who require reliable, high-quality chiral synthons for complex molecule construction.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system and other therapeutic areas.
• Asymmetric Synthesis: Utilized as a chiral auxiliary or ligand in catalytic asymmetric reactions to induce stereoselectivity.
• Peptidomimetics Research: Serves as a constrained amino acid analog for the design and synthesis of novel peptide-like molecules with enhanced stability and biological activity.
• Agrochemical Development: Used in the research and production of chiral pesticides and herbicides where specific stereochemistry is crucial for efficacy and environmental safety.
• Chemical Biology Probes: Incorporated into molecular probes for studying enzyme mechanisms and protein-ligand interactions.
• Academic & Industrial R&D: A valuable compound for methodological development in organic chemistry and for exploring new synthetic routes to complex natural products.

Basic Information

Product Name	2-Piperidinecarboxylicacid,3-Hydroxy-,(2R,3S)-(9Ci)
CAS No.	119593-44-1
Molecular Formula	C6H11NO3
Molecular Weight	145.16 g/mol
Synonyms	(2R,3S)-3-Hydroxypipecolic Acid; (2R,3S)-3-Hydroxy-2-piperidinecarboxylic Acid; (2R,3S)-3-Hydroxypipecolate; 3-Hydroxy-D-proline (piperidine analog); cis-3-Hydroxypipecolic Acid; (2R,3S)-3-Hydroxy-pipecolic acid; 3-Hydroxy-L-pipecolic acid (stereoisomer); 2-Carboxy-3-hydroxypiperidine
EINECS	Contact for details

Quality Control

Every batch of 2-Piperidinecarboxylicacid,3-Hydroxy-,(2R,3S)-(9Ci) is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure identity, purity, and stereochemical integrity, meeting the exacting standards required for pharmaceutical R&D and cGMP applications. A Certificate of Analysis (COA) detailing specifications such as chiral purity, chemical purity (HPLC), and residual solvents is available for each lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (2R,3S)
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.