Description

Cyclohexanecarboxylic Acid, 2-Hydroxy-, Ethyl Ester, (1S,2R)- is a high-purity, stereochemically defined chiral building block essential for advanced organic synthesis. This compound matters because its specific (1S,2R) configuration provides the precise three-dimensional structure required for synthesizing enantiomerically pure pharmaceuticals and fine chemicals. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs), particularly in central nervous system and cardiovascular drug candidates.
• Asymmetric Synthesis: Used as a chiral auxiliary or resolving agent in stereoselective reactions to control the formation of new stereocenters.
• Agrochemical Research: Serves as a building block for developing novel, optically active herbicides, fungicides, and plant growth regulators with improved efficacy and environmental profiles.
• Ligand and Catalyst Development: Employed in the preparation of chiral ligands for transition metal catalysis, enabling more efficient and selective industrial-scale chemical transformations.
• Flavor and Fragrance Industry: Potential precursor for the synthesis of complex, natural-identical odorants and flavor compounds requiring specific stereochemistry.
• Academic and R&D Laboratories: A valuable reagent for methodological studies in organic chemistry and the development of new synthetic pathways.

Basic Information

Product Name	Cyclohexanecarboxylic Acid, 2-Hydroxy-, Ethyl Ester, (1S,2R)-
CAS No.	119068-37-0
Molecular Formula	C10H18O3
Molecular Weight	186.25 g/mol
Synonyms	(1S,2R)-Ethyl 2-Hydroxycyclohexanecarboxylate; (-)-trans-Ethyl 2-Hydroxycyclohexanecarboxylate; (1S,2R)-2-Hydroxycyclohexanecarboxylic Acid Ethyl Ester; trans-(1S,2R)-Ethyl 2-Hydroxycyclohexanecarboxylate; Ethyl (1S,2R)-2-Hydroxycyclohexanecarboxylate; (1S,2R)-Ethyl 2-Hydroxy-1-cyclohexanecarboxylate; Chiral Ethyl 2-Hydroxycyclohexanecarboxylate
EINECS	Contact for details

Quality Control

Our Cyclohexanecarboxylic Acid, 2-Hydroxy-, Ethyl Ester, (1S,2R)- is manufactured under strict quality management systems to ensure batch-to-batch consistency and high enantiomeric purity. We provide comprehensive analytical data, including chiral HPLC analysis to confirm the (1S,2R) configuration and optical purity. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available for every batch and supplied with each order.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture. Store away from strong bases and incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Specific Rotation	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.