Description

L-Ornithine-Carboxy-14C Hydrochloride is a carbon-14 labeled derivative of the amino acid ornithine, specifically radiolabeled at the carboxyl carbon position. This compound is a critical tool for metabolic and pharmacokinetic studies, enabling researchers to precisely track the absorption, distribution, metabolism, and excretion (ADME) of ornithine and related compounds. It is essential for scientists in pharmaceutical R&D, biochemistry, and nutritional research who require high-specific-activity tracers for sensitive detection and quantification in complex biological systems.

Application

• Drug Metabolism and Pharmacokinetics (DMPK) Studies: Used as a radiolabeled tracer to investigate the metabolic pathways, bioavailability, and clearance of ornithine-based pharmaceuticals and nutraceuticals.
• Biochemical Pathway Analysis: Essential for tracing the incorporation of ornithine into the urea cycle, polyamine biosynthesis (putrescine, spermidine, spermine), and other critical metabolic routes in vitro and in vivo.
• Nutritional Research: Employed to study the metabolism, tissue distribution, and functional role of ornithine in sports nutrition, wound healing, and liver health applications.
• Diagnostic Agent Development: Serves as a precursor for synthesizing carbon-14 labeled probes for diagnostic imaging and research into metabolic disorders.
• Environmental Fate Studies: Applied in research to understand the environmental degradation and persistence of ornithine-containing compounds.

Basic Information

Product Name	L-Ornithine-Carboxy-14C Hydrochloride
CAS No.	117961-28-1
Molecular Formula	C5H1214CN2O2 • HCl
Molecular Weight	~184.6 g/mol (for unlabeled form; exact mass varies with specific activity)
Synonyms	(2S)-2,5-Diaminopentanoic-5-14C acid hydrochloride; L-2,5-Diaminovaleric-5-14C acid hydrochloride; Ornithine-5-14C hydrochloride; (S)-Ornithine-5-14C hydrochloride; L-Ornithine-5-14C monohydrochloride; (S)-2,5-Diaminopentanoic-5-14C acid hydrochloride; [carboxy-14C]-L-Ornithine hydrochloride
EINECS	Contact for details

Quality Control

Every batch of L-Ornithine-Carboxy-14C Hydrochloride is manufactured and analyzed under strict quality systems. We guarantee high chemical and radiochemical purity, with comprehensive testing for identity, specific activity, and radiochemical impurities. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting all critical parameters to ensure reproducibility and reliability for your research. Our quality commitment supports compliance with GLP (Good Laboratory Practice) standards.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive); containers should be allowed to equilibrate to room temperature before opening to minimize moisture uptake. For long-term storage, keep the primary container within a sealed secondary container.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS, NMR)	Conforms to structure
Assay (HPLC)	≥ 98% (chemical purity)
Radiochemical Purity (HPLC)	≥ 97%
Specific Activity	50-60 mCi/mmol (Custom activities available)
Solvent (for solution formats)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.