Description

Rac Clavam-2-Carboxylate Sodium Salt is a key pharmaceutical intermediate and a derivative of clavulanic acid. This compound is essential for the research, development, and synthesis of β-lactamase inhibitors, which are critical in combating antibiotic resistance. It serves as a vital building block for pharmaceutical manufacturers and research institutions focused on advanced antibiotic formulations and novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Primary use in the synthesis of clavulanate salts and other β-lactamase inhibitor APIs.
• Antibiotic Research & Development: A crucial precursor in R&D for novel combination antibiotics (e.g., amoxicillin/clavulanate formulations).
• Chemical Synthesis: Used in organic synthesis for constructing the oxazolidine ring system characteristic of clavams.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical labs.
• Biochemical Studies: Employed in enzymatic studies to investigate the mechanism of β-lactamase inhibition.

Basic Information

Item	Details
Product Name	Rac Clavam-2-Carboxylate Sodium Salt
CAS No.	117957-44-5
Molecular Formula	C8H8NNaO5
Molecular Weight	221.14 g/mol
Synonyms	Sodium (2R,5R)-3,3-dimethyl-7-oxo-4-oxa-1-azabicyclo[3.2.0]heptane-2-carboxylate; Clavulanic Acid Impurity C Sodium Salt; Sodium Clavam-2-Carboxylate; (2R,5R)-Clavam-2-carboxylic Acid Sodium Salt; Rac Sodium Clavam-2-Carboxylate; Clavulanate Sodium Related Compound C; 4-Oxa-1-azabicyclo[3.2.0]heptane-2-carboxylic Acid, 3,3-dimethyl-7-oxo-, Sodium Salt, (2R,5R)-
EINECS	Contact for details

Quality Control

Our Rac Clavam-2-Carboxylate Sodium Salt is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets stringent specifications for pharmaceutical intermediate use. Certificates of Analysis (COA) documenting all test results are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.