Description

4-Aminobenzoic Acid, [3,5-3H] is a tritium-labeled derivative of para-aminobenzoic acid (PABA), a key biochemical building block. This labeled compound is essential for advanced research requiring high-sensitivity detection and metabolic pathway tracing. It is primarily utilized by pharmaceutical, agrochemical, and academic research institutions engaged in drug development, biochemical studies, and analytical method validation.

Application

• Tracer Studies in Drug Metabolism & Pharmacokinetics (DMPK): Used to investigate the absorption, distribution, metabolism, and excretion (ADME) of PABA-related compounds and folate synthesis pathways.
• Biochemical Research: Serves as a radiolabeled precursor in enzymatic studies and the biosynthesis of more complex labeled molecules.
• Analytical Method Development: Acts as an internal standard or reference material in Liquid Chromatography-Mass Spectrometry (LC-MS) and other chromatographic assays for quantitative analysis.
• Agrochemical Research: Employed in studies to understand the environmental fate and metabolic pathways of certain herbicides and plant growth regulators.
• Material Science Research: Used in the development and testing of novel polymers and UV-absorbing materials where PABA is a component.

Basic Information

Product Name	4-Aminobenzoic Acid, [3,5-3H]
CAS No.	117610-59-0
Molecular Formula	C7H53H2NO2
Molecular Weight	~139.1 g/mol (for C73H7NO2)
Synonyms	PABA-[3,5-3H]; Tritiated 4-Aminobenzoic Acid; [3,5-3H]PABA; 4-Amino[3,5-3H]benzoic acid; para-Aminobenzoic Acid-3,5-3H; Vitamin B10 (labeled); Vitamin Bx (labeled); 4-Carboxyaniline-3,5-3H
EINECS	Contact for details

Quality Control

Every batch of our 4-Aminobenzoic Acid, [3,5-3H] is manufactured and analyzed under strict quality systems to ensure high chemical and radiochemical purity, specific activity, and stability. Our quality commitment includes rigorous analytical testing via HPLC, NMR, and radiometric detection methods. A comprehensive Certificate of Analysis (COA) detailing purity, specific activity (Ci/mmol or GBq/mmol), solvent, and analytical methods is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at recommended temperatures (typically 2-8°C or as specified on the label) in a designated, well-ventilated area for radioactive materials. Follow all local and international regulations for the handling and storage of radioactive compounds.

Specification

Item	Specification
Appearance	White to off-white solid or solution (as specified)
Identification (IR/NMR)	Conforms to structure
Chemical Purity (HPLC)	≥ 98%
Radiochemical Purity	≥ 97%
Specific Activity	10-30 Ci/mmol (Contact for exact value)
Solvent	Ethanol, Toluene, or as specified
Concentration	1 mCi/mL (or as specified)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.