Description

3-Cyano-2,4-Dichloro-5-Fluorobenzoylchloride is a highly functionalized benzoyl chloride derivative, serving as a critical advanced pharmaceutical intermediate (API) and versatile building block in organic synthesis. Its unique structure, featuring cyano, chloro, fluoro, and acid chloride functionalities, makes it indispensable for constructing complex molecules with specific electronic and steric properties. This compound is primarily sought after by R&D and production teams in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in fluorinated drug candidates targeting various therapeutic areas.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, where the fluorine and chlorine atoms enhance biological activity and environmental stability.
• Material Science Precursor: Serves as a monomer or cross-linking agent in the development of specialty polymers and high-performance materials.
• Ligand and Catalyst Development: Employed in organic and organometallic chemistry to create novel ligands for catalytic systems.
• Dye and Pigment Manufacturing: Acts as an intermediate in the synthesis of complex, color-fast dyes and organic pigments.
• Custom Synthesis and R&D: A valuable reagent for contract research organizations (CROs) and academic laboratories engaged in exploratory chemistry and method development.

Basic Information

Product Name	3-Cyano-2,4-Dichloro-5-Fluorobenzoylchloride
CAS No.	117528-59-3
Molecular Formula	C8Cl3FNO
Molecular Weight	262.44 g/mol
Synonyms	2,4-Dichloro-5-fluorobenzoyl cyanide chloride; 5-Fluoro-2,4-dichloro-3-cyanobenzoyl chloride; Benzoyl chloride, 3-cyano-2,4-dichloro-5-fluoro-; 3-Cyano-2,4-dichloro-5-fluorobenzoic acid chloride
EINECS	Contact for details

Quality Control

Our production of 3-Cyano-2,4-Dichloro-5-Fluorobenzoylchloride adheres to stringent quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We support our global partners with full traceability and documentation in line with cGMP and ISO standards where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature and reactivity as an acid chloride, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening. Isolate from strong bases, oxidizing agents, and alcohols.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.