Description

Eicosapentaenoic Acid [5,6,8 9,11,12,14,15,17,18-3 H] is a high-purity, tritium-labeled derivative of the essential ω-3 fatty acid, eicosapentaenoic acid (EPA). This labeled compound is critical for advanced metabolic and pharmacokinetic studies, providing researchers with a powerful tracer tool. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and analytical laboratories specializing in lipid metabolism, drug discovery, and nutritional science.

Application

• Metabolic Tracer Studies: Used as a radiolabeled tracer to investigate the absorption, distribution, metabolism, and excretion (ADME) of EPA and its derivatives in biological systems.
• Drug Discovery & Development: Essential for preclinical studies of novel lipid-based therapeutics, enabling precise tracking of drug candidates and their metabolites.
• Biochemical Pathway Analysis: Facilitates the elucidation of complex biochemical pathways involving ω-3 fatty acids, including eicosanoid biosynthesis and membrane lipid turnover.
• Analytical Reference Standard: Serves as a critical internal standard in Liquid Chromatography-Mass Spectrometry (LC-MS) and other analytical methods for the quantitative analysis of EPA.
• Nutritional Research: Employed in studies examining the specific metabolic fate and health benefits of EPA from dietary sources or supplements.

Basic Information

Product Name	Eicosapentaenoic Acid [5,6,8 9,11,12,14,15,17,18-3 H]
CAS No.	117396-78-8
Molecular Formula	C₂₀H₂₉³H₉O₂
Molecular Weight	~317.5 g/mol (³H-labeled)
Synonyms	EPA-[³H]; [5,6,8,9,11,12,14,15,17,18-³H]Eicosapentaenoic Acid; All-cis-5,8,11,14,17-Eicosapentaenoic Acid (tritiated); Tritium-Labeled EPA; ³H-EPA; (5Z,8Z,11Z,14Z,17Z)-5,8,11,14,17-Eicosapentaenoic Acid (tritiated); Icosapentaenoic Acid-[³H]; Timnodonic Acid-[³H]
EINECS	Contact for details

Quality Control

Every batch of our tritium-labeled compounds is produced and analyzed under stringent quality protocols to ensure high chemical and radiochemical purity, essential for sensitive research applications. Our quality commitment includes verification by advanced techniques such as HPLC and NMR. A comprehensive Certificate of Analysis (COA) detailing specific activity, purity, and solvent information is provided with each shipment to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to minimize radiolytic decomposition and oxidation. For long-term storage, solutions in appropriate organic solvents are recommended.

Specification

Item	Specification
Appearance	Colorless to pale yellow solution (typically in ethanol or toluene)
Identification (NMR/IR)	Conforms to structure
Chemical Purity (HPLC)	≥ 95%
Radiochemical Purity (HPLC)	≥ 97%
Specific Activity	Customizable (e.g., 10-100 Ci/mmol)
Concentration	1.0 mCi/mL (or as specified)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.