Description

5-(Trifluoromethyl)Benzene-1,3-Dicarboxylic Acid is a high-purity aromatic dicarboxylic acid derivative, distinguished by the presence of a trifluoromethyl group which imparts unique electronic and steric properties. This compound is a critical advanced pharmaceutical intermediate and a versatile building block for the synthesis of complex organic molecules. It is primarily utilized by R&D chemists and process development teams in the pharmaceutical, agrochemical, and specialty polymer industries.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring a rigid, lipophilic aromatic core with enhanced metabolic stability.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where the trifluoromethyl group can improve biological activity and environmental persistence.
• Ligand and Catalyst Design: Serves as a backbone for constructing polydentate ligands in coordination chemistry and catalysis, especially for metal-organic frameworks (MOFs).
• Polymer & Material Science: Acts as a monomer for producing high-performance polyamides, polyesters, and polyimides with enhanced thermal stability and chemical resistance.
• Organic Electronic Materials: Employed in the research and development of organic semiconductors and light-emitting materials due to its electron-withdrawing character.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis projects and fine chemical production under cGMP or ISO standards.

Basic Information

Product Name	5-(Trifluoromethyl)Benzene-1,3-Dicarboxylic Acid
CAS No.	117186-03-5
Molecular Formula	C9H5F3O4
Molecular Weight	234.13 g/mol
Synonyms	5-(Trifluoromethyl)isophthalic Acid; 1,3-Benzenedicarboxylic acid, 5-(trifluoromethyl)-; Trifluoromethylisophthalic Acid; 5-Carboxy-3-(trifluoromethyl)benzoic acid; α,α,α-Trifluoro-5-carboxyisophthalic acid; Isophthalic acid, 5-trifluoromethyl-; 5-Trifluoromethyl-1,3-benzenedicarboxylic acid
EINECS	Contact for details

Quality Control

Our 5-(Trifluoromethyl)Benzene-1,3-Dicarboxylic Acid is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing to ensure it meets the highest standards of purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed to prevent absorption of atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.