Description

1-Fluorocyclohexanecarboxylic Acid is a versatile fluorinated building block characterized by a carboxylic acid group attached to a fluorinated cyclohexane ring. This unique structure makes it a valuable intermediate for introducing both fluorine atoms and carboxylic acid functionality into more complex molecules, enhancing their metabolic stability and binding properties. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and advanced material synthesis.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in creating fluorinated analogs to improve drug potency and bioavailability.
• Agrochemical Research: Used in the synthesis of advanced herbicides, fungicides, and pesticides where the fluorine moiety can increase biological activity and environmental persistence.
• Liquid Crystal & Material Science: Serves as a precursor for fluorinated monomers and polymers used in specialty materials, coatings, and liquid crystal displays (LCDs).
• Organic Synthesis Building Block: Employed in various organic transformations, including esterification, amidation, and decarboxylative coupling reactions to construct complex molecular architectures.
• Fluorine-19 NMR Spectroscopy: Can be utilized as a standard or probe molecule in analytical chemistry due to the distinct NMR signal of the fluorine atom.

Basic Information

Product Name	1-Fluorocyclohexanecarboxylic Acid
CAS No.	117169-31-0
Molecular Formula	C7H11FO2
Molecular Weight	146.16 g/mol
Synonyms	Cyclohexanecarboxylic acid, 1-fluoro-; 1-Fluorocyclohexane-1-carboxylic acid; Fluorocyclohexanecarboxylic acid; (Fluorocyclohexyl)carboxylic acid; 1-Fluoro-1-cyclohexanecarboxylic acid; 1-Fluorocyclohexylcarboxylic acid; NSC 405124
EINECS	Contact for details

Quality Control

Our 1-Fluorocyclohexanecarboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Melting Point	Contact for details
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.