Description

L-Fructose-1-13C is a stable isotope-labeled analog of fructose, a fundamental monosaccharide. This product is essential for advanced metabolic research and analytical method development, providing a precise tracer for tracking carbon-1 pathways. It is primarily used by researchers and manufacturers in the pharmaceutical, nutritional science, and diagnostic industries for applications requiring high isotopic purity and chemical stability.

Application

• Metabolic Pathway Tracing: Used as a 13C-labeled tracer in in vitro and in vivo studies to elucidate fructose metabolism, glycolysis, and the pentose phosphate pathway.
• Pharmaceutical Research: Critical for drug metabolism studies (DMPK) to understand the pharmacokinetics and metabolic fate of carbohydrate-based therapeutics.
• Clinical Diagnostics: Serves as a key component in the development of internal standards for mass spectrometry-based assays, enhancing accuracy in measuring fructose levels in biological fluids.
• Nutritional Science: Enables precise research into dietary sugar absorption, utilization, and their role in metabolic disorders such as diabetes and obesity.
• NMR Spectroscopy: Employed as a standard or probe in Nuclear Magnetic Resonance (NMR) studies due to its distinct 13C signal, facilitating structural and dynamic analysis of biomolecules.
• Biochemical Reagent Manufacturing: Incorporated into specialized kits and reagents for enzymatic assays and research-grade biochemicals.

Basic Information

Product Name	L-Fructose-1-13C
CAS No.	117013-21-5
Molecular Formula	C6H12O6 (with 13C at position 1)
Molecular Weight	181.16 g/mol (for 13C1 isotopologue)
Synonyms	(1-13C)-Fructose; 1-13C-Fructose; Fructose-1-13C; Levulose-1-13C; D-(-)-Fructose-1-13C; (3S,4R,5R)-1,3,4,5,6-Pentahydroxyhexan-2-one-1-13C; 13C Labeled Fructose; Stable Isotope Labeled Fructose
EINECS	Contact for details

Quality Control

Our L-Fructose-1-13C is manufactured under strict quality systems to ensure high isotopic and chemical purity suitable for sensitive research applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing parameters such as isotopic enrichment, chemical purity, and absence of specific impurities. We adhere to relevant industry guidelines for stable isotope-labeled compounds to ensure reliable and reproducible performance in your experiments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent absorption of atmospheric moisture, which can affect stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Isotopic Enrichment	≥ 99 atom % 13C
Assay (HPLC)	≥ 98.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Specific Optical Rotation	-90° to -94° (c=1 in H2O)
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.