Description

n-Phenyltetrafluorophthalimide is a high-purity, specialized fluorinated organic intermediate. This compound matters for its role as a key building block in the synthesis of advanced materials and active pharmaceutical ingredients (APIs), where its unique fluorinated aromatic structure imparts desirable properties like enhanced stability and lipophilicity. It is primarily needed by R&D chemists and process development teams in the pharmaceutical, agrochemical, and specialty polymer industries seeking to innovate with fluorine chemistry.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of fluorinated drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the development of novel herbicides and pesticides, where the fluorine atoms can improve biological activity and environmental persistence.
• Advanced Material Monomer: Serves as a building block for high-performance polymers, such as polyimides, which are valued for their thermal stability and chemical resistance in electronics and aerospace.
• Liquid Crystal & OLED Materials: Incorporated into the molecular structure of fluorinated liquid crystals and organic light-emitting diode (OLED) materials to optimize electronic properties and performance.
• Organic Synthesis Reagent: Acts as a versatile reagent in organic synthesis for introducing the phthalimide protecting group or the fluorinated phenyl moiety into complex molecules.
• Research & Development: Essential for academic and industrial research exploring new reactions and properties of fluorinated heterocyclic compounds.

Basic Information

Product Name	n-Phenyltetrafluorophthalimide
CAS No.	116508-58-8
Molecular Formula	C₁₄H₅F₄NO₂
Molecular Weight	295.19 g/mol
Synonyms	N-Phenyltetrafluorophthalimide; 4,5,6,7-Tetrafluoro-N-phenyl-1H-isoindole-1,3(2H)-dione; 1H-Isoindole-1,3(2H)-dione, 4,5,6,7-tetrafluoro-N-phenyl-; Tetrafluorophthalimide N-phenyl derivative; Phenyltetrafluorophthalimide; N-Phenyl-4,5,6,7-tetrafluorophthalimide
EINECS	Contact for details

Quality Control

Our n-Phenyltetrafluorophthalimide is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided for each shipment, supporting compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.