Description

D-Mannose-6-13C is a stable isotope-labeled analog of D-Mannose, specifically enriched with carbon-13 at the 6-position. This high-purity labeled compound is essential for advanced research and analytical applications where precise metabolic tracing is required. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and diagnostic sectors for applications such as metabolic pathway studies, quantitative mass spectrometry, and the development of internal standards.

Application

• Isotopic Tracer in Metabolic Research: Used in in vitro and in vivo studies to trace the metabolic fate of mannose and related glycans in biological systems.
• Quantitative Mass Spectrometry (MS): Serves as a critical internal standard for the accurate quantification of endogenous D-mannose and its metabolites via LC-MS or GC-MS.
• Pharmaceutical Development: Employed in the research and development of glycoprotein-based therapeutics and carbohydrate-related drugs.
• Biochemical Pathway Analysis: Facilitates the study of glycosylation pathways, congenital disorders of glycosylation (CDG), and carbohydrate metabolism.
• Diagnostic Reagent Manufacturing: Used in the formulation of high-precision diagnostic kits and assays for metabolic disorders.
• NMR Spectroscopy: Acts as a valuable probe in nuclear magnetic resonance (NMR) studies for structural and dynamic analysis of carbohydrate interactions.

Basic Information

Product Name	D-Mannose-6-13C
CAS No.	115973-81-4
Molecular Formula	C513CH12O6
Molecular Weight	181.15 g/mol (for 13C1)
Synonyms	D-Mannose-6-13C; (6-13C)-D-Mannose; Mannose-6-13C; 6-13C-D-Mannopyranose; D-(+)-Mannose-6-13C; 6-Carbon-13 Labeled D-Mannose; Mannose (6-13C); Stable Isotope-Labeled D-Mannose
EINECS	Contact for details

Quality Control

Our D-Mannose-6-13C is manufactured under strict quality systems to ensure exceptional isotopic and chemical purity. Each batch is subjected to rigorous analytical testing, including NMR for isotopic enrichment verification and HPLC for chemical purity assessment. A comprehensive Certificate of Analysis (COA) detailing isotopic purity (atom % 13C), chemical purity, and specific analytical data is provided with every shipment to guarantee traceability and compliance with research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccated conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Isotopic Purity (Atom % 13C)	≥ 99% (at C-6)
Chemical Purity (HPLC)	≥ 98.0%
Specific Optical Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.