Description

Pindolol-Nbd is a high-purity, fluorescent-labeled derivative of the β-blocker pindolol, specifically designed for advanced research applications. This compound is critical for scientists requiring precise, sensitive detection and quantification in complex biological matrices. It serves as an essential tool for researchers in pharmaceutical development, biochemical analysis, and receptor binding studies, enabling detailed investigation of drug interactions and metabolic pathways.

Application

• Biochemical Research & Assay Development: Used as a fluorescent probe in competitive binding assays and fluorescence polarization (FP) assays to study β-adrenergic receptor interactions.
• Pharmaceutical R&D: Acts as a key analytical standard and tracer in the development and validation of bioanalytical methods for pindolol and its metabolites.
• Metabolic Pathway Studies: Employed to visualize and track the distribution and localization of pindolol in cellular and tissue studies.
• High-Throughput Screening (HTS): Utilized in fluorescence-based HTS platforms to identify and characterize new therapeutic compounds targeting related pathways.
• Quality Control & Reference Standard: Serves as a certified reference material (CRM) for ensuring the accuracy and precision of analytical results in quality control laboratories.

Basic Information

Product Name	Pindolol-Nbd
CAS No.	115910-09-3
Molecular Formula	C24H28N4O5
Molecular Weight	452.50 g/mol
Synonyms	4-(2-Hydroxy-3-[(1-methylethyl)amino]propoxy)-N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)indole; Pindolol labeled with NBD; Pindolol-NBD conjugate; NBD-Pindolol; 7-Nitrobenz-2-oxa-1,3-diazol-4-yl Pindolol; Fluorescent Pindolol Derivative; Pindolol NBD analog
EINECS	Contact for details

Quality Control

Every batch of Pindolol-Nbd is manufactured under strict quality management protocols and undergoes comprehensive analytical testing. We ensure compliance with high-purity research-grade standards, with key parameters verified by HPLC, NMR, and mass spectrometry. A detailed Certificate of Analysis (COA) containing batch-specific data for identity, purity, and related substances is provided with each shipment to guarantee traceability and reliability for your critical research.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dedicated freezer. Allow the sealed vial to equilibrate to room temperature before opening to minimize condensation and moisture uptake. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Yellow to orange solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	≤ 5.0% total
Water Content (KF)	≤ 1.0%
Solubility	Soluble in DMSO, DMF; sparingly soluble in methanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.