Description

2-Bromo-6-(Glutathion-S-Yl)Hydroquinone is a specialized biochemical reagent of significant interest in advanced research and development. This compound matters as a key metabolite and reference standard for studying quinone-thiol interactions, glutathione conjugation pathways, and associated oxidative stress mechanisms. It is primarily needed by researchers and developers in the pharmaceutical, toxicology, and biochemical sectors for investigating drug metabolism, reactive intermediate formation, and cellular redox biology.

Application

• Biochemical Research: Used as a critical reference standard and metabolite in studies of quinone metabolism and glutathione (GSH) conjugation pathways.
• Toxicology Studies: Employed to investigate the formation and reactivity of brominated quinone metabolites and their potential role in chemical toxicity and oxidative stress.
• Pharmaceutical Development: Serves as a tool compound for understanding the metabolic fate of brominated compounds and designing safer drug candidates.
• Analytical Chemistry: Utilized as a high-purity standard for method development and validation in HPLC, LC-MS, and other analytical techniques targeting thiol-quinone adducts.
• Redox Biology: Applied in research focused on cellular antioxidant defense systems and the interplay between electrophiles and nucleophilic thiols like glutathione.

Basic Information

Product Name	2-Bromo-6-(Glutathion-S-Yl)Hydroquinone
CAS No.	114865-64-4
Molecular Formula	C16H21BrN3O8S
Molecular Weight	495.32 g/mol
Synonyms	2-Bromo-6-(glutathion-S-yl)hydroquinone; 2-Bromo-6-(GS-yl)hydroquinone; 2-Bromo-6-S-glutathionylhydroquinone; BHQ-SG; Bromohydroquinone-glutathione conjugate; Glutathionyl-bromohydroquinone; 1,4-Benzenediol, 2-bromo-6-[[(2S)-1-[(carboxymethyl)amino]-5-[[(2R)-1-[(1S)-2-amino-2-carboxyethyl]amino]-1-oxo-3-sulfanyl-2-propanyl]amino]-1-oxo-3-sulfanyl-2-propanyl]amino]-1-oxo-3-sulfanyl-2-propanyl]amino]-1-oxo-2-propanyl]-, (S)-
EINECS	Contact for details

Quality Control

Our 2-Bromo-6-(Glutathion-S-Yl)Hydroquinone is produced and handled under strict quality protocols to ensure batch-to-batch consistency and reliability for research applications. All materials are characterized using advanced analytical techniques, including NMR and mass spectrometry, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) for long-term stability. This compound is both light-sensitive (store away from light) and hygroscopic (moisture-sensitive). Allow the sealed container to equilibrate to room temperature before opening to minimize moisture ingress. For short-term use, store desiccated at 2-8°C.

Specification

Item	Specification
Appearance	Off-white to light tan solid
Identification (HPLC)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥ 95%
Assay	≥ 90% (by HPLC)
Water Content	≤ 2.0% (KF)
Solubility	Soluble in DMSO, Methanol; Slightly soluble in Water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.