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2-Chloro-2',3'-Dideoxyadenosine CAS NO 114849-58-0


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CAS No.:114849-58-0

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

2-Chloro-2',3'-Dideoxyadenosine is a modified nucleoside analog of significant interest in pharmaceutical research and development. This compound serves as a crucial synthetic intermediate and a potential pharmacologically active agent. It is primarily utilized by research institutions and pharmaceutical companies engaged in the synthesis of antiviral and anticancer drug candidates.

Application

  • Pharmaceutical Intermediate: Key building block in the synthesis of novel nucleoside-based therapeutics.
  • Antiviral Research: Investigated for its potential activity against various viral targets, including retroviruses.
  • Anticancer Agent Development: Studied for its mechanism of action and efficacy in oncology research programs.
  • Biochemical Tool: Used in enzymatic studies and as a substrate analog to understand nucleoside metabolism.
  • Organic Synthesis: Valuable precursor for further chemical modifications to create libraries of related analogs.
  • Life Science Research: Employed in academic and industrial labs for fundamental studies in medicinal chemistry.

Basic Information

Product Name 2-Chloro-2',3'-Dideoxyadenosine
CAS No. 114849-58-0
Molecular Formula C10H11ClN5O2
Molecular Weight 268.68 g/mol
Synonyms 2-Chloro-ddA; 2-Cl-ddA; 2-Chloro-2',3'-dideoxyadenosine; 9-[(2R,5S)-5-(Chloromethyl)oxolan-2-yl]-9H-purin-6-amine; 2-Chloro-2',3'-dideoxy-adenosine; 2-Chloro-2',3'-ddA; 2-Cl-2',3'-dideoxyadenosine; 2-Chloro-9-(2,3-dideoxy-β-D-glycero-pent-2-enofuranosyl)adenine
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Quality Control

Our 2-Chloro-2',3'-Dideoxyadenosine is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to relevant industry standards for fine chemical production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item Specification
Appearance White to off-white powder
Identification (IR) Conforms to structure
Identification (HPLC) Retention time matches reference standard
Purity (HPLC) ≥ 98.0%
Water Content (KF) ≤ 1.0%
Residue on Ignition ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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