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β-D-Glucopyranosiduronic Acid, (3α,5β,17β)-17-Hydroxyandrostan-3-Yl (9Ci) CAS NO 114761-91-0


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CAS No.:114761-91-0

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

β-D-Glucopyranosiduronic Acid, (3α,5β,17β)-17-Hydroxyandrostan-3-Yl (9Ci) is a high-purity steroid conjugate, specifically a glucuronide derivative of a hydroxyandrostane. This compound serves as a critical reference standard and synthetic intermediate in pharmaceutical research and development. It is primarily required by pharmaceutical R&D laboratories, contract research organizations (CROs), and manufacturers of active pharmaceutical ingredients (APIs) for analytical method development, metabolic studies, and the synthesis of novel therapeutic agents.

Application

  • Pharmaceutical Reference Standard: Used for the identification, purity assessment, and quantification in analytical methods such as HPLC and LC-MS for drug development and quality control.
  • Metabolite Synthesis & Research: Acts as a key intermediate or model compound in studying steroid metabolism and the formation of glucuronide conjugates.
  • Biochemical Research: Employed in enzymatic studies, particularly those involving glucuronosyltransferases, to understand drug detoxification pathways.
  • API Intermediate: Serves as a building block in the multi-step synthesis of complex steroid-based active pharmaceutical ingredients.
  • Doping Control Analysis: Utilized as a calibrant or control substance in sports anti-doping laboratories for the detection of synthetic anabolic agents and their metabolites.
  • Academic Research: Used in university and institutional labs for fundamental research in organic chemistry, medicinal chemistry, and endocrinology.

Basic Information

Product Name β-D-Glucopyranosiduronic Acid, (3α,5β,17β)-17-Hydroxyandrostan-3-Yl (9Ci)
CAS No. 114761-91-0
Molecular Formula C25H38O8
Molecular Weight 466.57 g/mol
Synonyms 17β-Hydroxy-5β-androstan-3α-yl β-D-glucopyranosiduronic acid; Etiocholanolone glucuronide (referencing the aglycone); 3α-Hydroxy-5β-androstan-17-one 3-glucuronide; 5β-Androstane-3α,17β-diol 3-glucuronide; Etiocholanolone 3-glucuronide; (3α,5β,17β)-3-(β-D-Glucopyranuronosyloxy)-17-hydroxyandrostane; Steroid glucuronide conjugate; Androstane glucuronide.
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Quality Control

Every batch of our β-D-Glucopyranosiduronic Acid, (3α,5β,17β)-17-Hydroxyandrostan-3-Yl (9Ci) is manufactured and analyzed under a strict quality management system. We provide comprehensive analytical data to ensure it meets the exacting standards for research and pharmaceutical applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are supplied with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item Specification
Appearance White to off-white powder
Identification (IR) Conforms to structure
Identification (HPLC) Retention time matches reference standard
Assay (HPLC) ≥ 98.0%
Water Content (KF) ≤ 2.0%
Residue on Ignition ≤ 0.1%
Related Substances (HPLC) Total impurities ≤ 2.0% Any single impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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