Description

3-(Glutathion-S-Yl)-1,4-Naphthoquinone is a specialized biochemical conjugate formed from the reaction of glutathione with 1,4-naphthoquinone. This compound is of significant interest in biochemical and toxicological research due to its role as a marker for metabolic pathways involving reactive quinone species. It is primarily utilized by research institutions and pharmaceutical development teams focused on oxidative stress, drug metabolism, and the study of detoxification mechanisms.

Application

• Biochemical Research: Used as a reference standard and probe in studies of glutathione conjugation and quinone metabolism.
• Toxicology Studies: Serves as a critical marker for investigating the metabolic activation and detoxification pathways of naphthoquinone-based compounds.
• Oxidative Stress Analysis: Employed in research models to understand cellular responses to oxidative damage and the role of the glutathione system.
• Pharmaceutical Development: Acts as an intermediate or reference material in the development of drugs targeting redox biology or metabolic disorders.
• Analytical Chemistry: Used as a standard for method development and validation in HPLC or LC-MS analyses of biological samples.

Basic Information

Product Name	3-(Glutathion-S-Yl)-1,4-Naphthoquinone
CAS No.	114576-98-6
Molecular Formula	C23H29N3O10S
Molecular Weight	539.56 g/mol
Synonyms	3-(Glutathion-S-yl)-1,4-naphthoquinone; 1,4-Naphthoquinone, 3-(glutathion-S-yl)-; Glutathione-1,4-naphthoquinone conjugate; GS-1,4-NQ; 3-(GSH-yl)-1,4-naphthoquinone; Naphthoquinone-glutathione adduct; 3-(L-γ-Glutamyl-L-cysteinylglycin-S-yl)-1,4-naphthoquinone
EINECS	Contact for details

Quality Control

Our 3-(Glutathion-S-Yl)-1,4-Naphthoquinone is produced under strict quality protocols suitable for research applications. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods. A Certificate of Analysis (COA) detailing batch-specific results is provided to ensure traceability and compliance with your research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. This material is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Yellow to orange solid
Identification (HPLC/UV)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Water Content	≤ 2.0%
Residual Solvents	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.