Description

Zalospirone CAS NO 114298-18-9 is a high-purity azapirone derivative and a selective 5-HT1A receptor agonist. This compound is of significant interest for its potential pharmacological activity in the research and development of novel therapeutic agents. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in neuropharmacology and central nervous system (CNS) drug discovery.

Application

• As a reference standard in analytical method development and validation for quality control laboratories.
• As a key pharmacological research tool for studying serotonin (5-HT1A) receptor function and signaling pathways.
• In preclinical drug discovery programs targeting anxiety, depression, and related CNS disorders.
• For the synthesis of more complex molecular entities or labeled analogs for metabolic and pharmacokinetic studies.
• As an intermediate in the development and scale-up of active pharmaceutical ingredients (APIs) within the azapirone class.

Basic Information

Product Name	Zalospirone
CAS No.	114298-18-9
Molecular Formula	C21H26N2O2
Molecular Weight	338.45 g/mol
Synonyms	Zalospirone; 4,4-Dimethyl-1-[4-[4-(2-pyrimidinyl)-1-piperazinyl]butyl]-2,6-piperidinedione; WY-47,846; WY 47846; WY47846; 1-[4-[4-(Pyrimidin-2-yl)piperazin-1-yl]butyl]-4,4-dimethylpiperidine-2,6-dione
EINECS	Contact for details

Quality Control

Our Zalospirone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification, purity assay, and impurity profiling, to ensure it meets stringent specifications for research and development use. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any individual impurity ≤ 0.5%
Total Impurities	≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.