Description

5'-o-Galactopyranosyl Ribavirin is a chemically modified nucleoside analog, specifically a galactosylated derivative of the broad-spectrum antiviral agent Ribavirin. This molecular modification is designed to alter the pharmacokinetic profile, potentially enhancing targeted delivery and reducing systemic side effects. It is a critical intermediate and research compound for pharmaceutical developers and academic institutions focused on advancing antiviral therapeutics and prodrug strategies.

Application

• Pharmaceutical Intermediate: Serves as a key synthetic precursor in the research and development of novel antiviral prodrugs.
• Antiviral Research: Used in biochemical and virological studies to investigate structure-activity relationships (SAR) and mechanisms of action against RNA viruses.
• Prodrug Development: Explored for its potential to improve the bioavailability and tissue-specific targeting of nucleoside-based antiviral agents.
• Bioconjugation Studies: Acts as a model compound in glycosylation chemistry and carbohydrate-drug conjugate research.
• Reference Standard: Employed as a high-purity analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	5'-o-Galactopyranosyl Ribavirin
CAS No.	114283-62-4
Molecular Formula	C15H23N5O10
Molecular Weight	433.37 g/mol
Synonyms	1-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1H-1,2,4-triazole-3-carboxamide, 5'-O-β-D-Galactopyranosyl Derivative; Ribavirin 5'-O-β-D-Galactopyranoside; Galactosylated Ribavirin; 1-β-D-Ribofuranosyl-1,2,4-triazole-3-carboxamide 5'-O-β-D-Galactopyranoside
EINECS	Contact for details

Quality Control

Every batch of 5'-o-Galactopyranosyl Ribavirin is manufactured and tested under strict quality management systems. We provide comprehensive analytical data to ensure identity, purity, and consistency, meeting the stringent requirements of research and development applications. A Certificate of Analysis (COA) detailing specifications such as assay (HPLC), related substances, residual solvents, and identification is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.