Description

S-(+)-Fluoxetine Hydrochloride CAS NO 114247-06-2 is the pharmacologically active enantiomer of the widely used selective serotonin reuptake inhibitor (SSRI). This high-purity chiral intermediate is critical for ensuring the efficacy and safety of advanced pharmaceutical formulations. It is primarily required by manufacturers in the pharmaceutical and fine chemical industries for the research, development, and production of enantiomerically pure active pharmaceutical ingredients (APIs).

Application

• Key chiral intermediate in the synthesis of enantiopure fluoxetine hydrochloride API.
• Research and development of novel SSRI-based therapeutics with improved pharmacological profiles.
• Production of reference standards and certified materials for analytical testing and quality control laboratories.
• Manufacturing of pharmaceutical formulations requiring the specific (S)-(+) enantiomer for targeted therapeutic effect.
• Process development and scale-up activities in contract manufacturing organizations (CMOs) serving the pharmaceutical sector.
• Academic and institutional research into neuropharmacology and chiral chemistry.

Basic Information

Product Name	S-(+)-Fluoxetine Hydrochloride
CAS No.	114247-06-2
Molecular Formula	C17H19F3NO • HCl
Molecular Weight	345.79 g/mol
Synonyms	(S)-Fluoxetine Hydrochloride; (S)-(+)-N-Methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propylamine Hydrochloride; (S)-Prozac Hydrochloride; (S)-N-Methyl-γ-[4-(trifluoromethyl)phenoxy]benzenepropanamine Hydrochloride; (3S)-3-(4-Trifluoromethylphenoxy)-3-phenylpropyl-methylamine Hydrochloride; (S)-Lilly 110140; (S)-Fluoxetine HCl
EINECS	Contact for details

Quality Control

Our S-(+)-Fluoxetine Hydrochloride is manufactured under strict quality systems to meet the exacting standards of the pharmaceutical industry. Each batch is subjected to comprehensive analytical testing, including chiral purity and impurity profile analysis, to ensure compliance with relevant pharmacopeial guidelines. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.5%
Chiral Purity (HPLC)	≥99.0% (S)-enantiomer
Related Substances (HPLC)	Total impurities ≤1.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.