Description

9-(3-Hydroxy-2-Phosphonomethoxypropyl)Guanine is a high-purity nucleotide analog with significant antiviral research and pharmaceutical development potential. This compound is valued for its role as a key intermediate in the synthesis of advanced antiviral agents, particularly those targeting DNA viruses. It is primarily utilized by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic research institutions engaged in developing novel therapeutic compounds.

Application

• Pharmaceutical Intermediate: Critical building block for the synthesis of antiviral prodrugs and nucleotide analogs.
• Antiviral Research: Used in biochemical and pharmacological studies to investigate mechanisms of action against herpesviruses and other DNA viruses.
• Active Pharmaceutical Ingredient (API) Development: Serves as a precursor in the manufacturing process for experimental antiviral medications.
• Biochemical Tool Compound: Employed in enzymatic assays and studies of viral polymerase inhibition.
• Reference Standard: Used as a certified reference material (CRM) for quality control and analytical method development in pharmaceutical analysis.

Basic Information

Product Name	9-(3-Hydroxy-2-Phosphonomethoxypropyl)Guanine
CAS No.	113852-36-1
Molecular Formula	C9H15N5O7P
Molecular Weight	327.22 g/mol
Synonyms	HPMPG; (S)-HPMPG; (S)-9-[3-Hydroxy-2-(phosphonomethoxy)propyl]guanine; Cidofovir Impurity; GS-504; Adefovir related compound; PMEG precursor; Antiviral nucleotide analog
EINECS	Contact for details

Quality Control

Our 9-(3-Hydroxy-2-Phosphonomethoxypropyl)Guanine is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, detailing purity, impurities, and other critical parameters relevant for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.